Results 21 to 30 of about 662,429 (302)

Calcineurin inhibitors in lupus nephritis [PDF]

Journal of Nephrology, 2020
n ...
Ponticelli C., Podesta M. A.
openaire   +4 more sources

Differential involvement of hippocampal calcineurin during learning and reversal learning in a Y-maze task [PDF]

, 2006
The regulation and function of the calcium-dependent phosphatase calcineurin (CaN, protein phosphatase 2B) in learning and memory remain unclear, although recent work indicates that CaN may play a differential role in training and reversal training.
Havekes, Robbert,, Luiten, Paul G. M., Havekes, Robbert, Nijholt, Ingrid M.,, van der Zee, Eddy A., Havekes, Robbert; id_orcid, Nijholt, Ingrid M., Luiten, Paul G.M.,, Zee, Eddy A. van der,   +8 more
core   +2 more sources

Calcineurin Is a Universal Regulator of Vessel Function—Focus on Vascular Smooth Muscle Cells

Cells, 2023
Calcineurin, a serine/threonine phosphatase regulating transcription factors like NFaT and CREB, is well known for its immune modulatory effects and role in cardiac hypertrophy.
Alexander Nolze, Sebastian Matern, Claudia Grossmann   +2 more
doaj   +1 more source

Calcineurin inhibitors: status quo and perspectives

Biomolecular Concepts, 2011
Despite the fact that cyclosporin A (CsA) and tacrolimus (FK506) are very potent drugs in the treatment of serious autoimmune diseases and in the prevention of graft vs.
Erdmann Frank, Weiwad Matthias
doaj   +1 more source

Atopic dermatitis: a review of topical nonsteroid therapy

Drugs in Context, 2018
Background: Atopic dermatitis is a chronic inflammatory skin condition that affects up to 20% of children and 3% of adults globally. Although topical corticosteroids are considered to be the first-line agents, they can be associated with cutaneous and ...
Ariana Papier, Lindsay C Strowd
doaj   +1 more source

The effect of early everolimus administration on the renal function while reducing the dosage of calcineurin inhibitors in liver transplant recipients in a long-term follow-up

Трансплантология (Москва), 2021
Introduction. The lifelong use of calcineurin inhibitors in liver transplant recipients leads to an increased incidence of chronic kidney disease.Objective.
V. E. Syutkin, A. A. Salienko, O. D. Olisov, S. V. Zhuravel, M. S. Novruzbekov   +4 more
doaj   +1 more source

TACROLIMUS ASSOCIATED HEMORRHAGIC POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME: A RARE CASE IN THE LATE PERIOD AFTER RENAL TRANSPLANTATION

İstanbul Tıp Fakültesi Dergisi, 2022
Immunosuppressive agents such as calcineurin inhibitors, which are commonly used in transplant patients may play a role in the development of posterior reversible encephalopathy syndrome (PRES), one of the rare neurological complications after organ and ...
Yasemin Akıncı, Nurhan Seyahi, Sabahattin Saip, Ayşegül Gündüz   +3 more
doaj   +1 more source

Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

Cell Reports, 2019
Summary: Calcineurin/NFAT signaling is active in endothelial cells and is proposed to be an essential component of the tumor angiogenic response.
Stefanie Hendrikx, Sanja Coso, Borja Prat-Luri, Laureline Wetterwald, Amélie Sabine, Claudio A. Franco, Sina Nassiri, Nadine Zangger, Holger Gerhardt, Mauro Delorenzi, Tatiana V. Petrova   +10 more
doaj   +1 more source

Inibidores de calcineurina no tratamento das dermatoses alérgicas Calcineurin inhibitors in the treatment of allergic dermatitis

Jornal de Pediatria, 2006
OBJETIVO: Revisar o papel dos inibidores da calcineurina no tratamento das dermatoses alérgicas, com ênfase nos mecanismos de ação, eficácia e efeitos adversos tópicos e sistêmicos.
Ana Paula Beltran Moschione Castro
doaj   +1 more source

Calcineurin inhibitors and calcineurin-NFAT system

Japanese Journal of Clinical Immunology, 2010
Cyclosporin A and tacrolimus have been used as immunosuppressive agents initially in organ transplantation after their discovery, and are also used for treatment of the autoimmune disease, providing an excellent therapeutic effect. These agents act targeting on intracellular phosphatase calcineurin (CN), and subsequently inhibit activation of nuclear ...
openaire   +3 more sources