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Frontiers in Cellular Neuroscience, 2023 How do neurons that implement cell-autonomous self-regulation of calcium react to knockout of individual ion-channel conductances? To address this question, we used a heterogeneous population of 78 conductance-based models of hippocampal pyramidal ...
Sunandha Srikanth +2 more
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CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A. [PDF]
PLoS ONE, 2018 The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (ICaCC), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate ICaCC by
Aarushi Sharma +4 more
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The role of calcium channel blockers in wound healing [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors.
Hoda Mojiri-Forushani
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Channels, 2023 One of nature’s exceptions was discovered when a Cav3 T-type channel was observed to switch phenotype from a calcium channel into a sodium channel by neutralizing an aspartate residue in the high field strength (HFS) +1 position within the ion ...
J. David Spafford
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Renoprotective effect of calcium channel blockers [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 The advancing chronic renal failure is at most the consequence of secondary haemodynamic and metabolic factors as intraglomerular hypertension and glomerular hypertrophy.
Dimković Nada, Dimković Siniša
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Critical Care Explorations, 2021 OBJECTIVES:. The aim was to evaluate the effect of dihydropyridine calcium channel blocker on the prognosis for moderate-severe pulmonary acute respiratory distress syndrome in hypertension patients. DESIGN:.
Fengyuan Li, MD +9 more
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Regulation of Presynaptic Calcium Channels by Synaptic Proteins
Journal of Pharmacological Sciences, 2003 Calcium entry into nerve termini via voltage gated calcium channels is an essential step in neurotransmission. Consequently, second messenger regulation of calcium channel activity modulates synaptic activity.
Gerald W. Zamponi
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Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
, 2018 Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan +10 more
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Calcium channel blockers- Induced iatrogenic gingival hyperplasia: Case series
Journal of Pharmacy and Bioallied Sciences, 2023 Hypertension rightfully termed as “Silent killer” is associated with increase in morbidity and mortality when left untreated. Calcium channel blockers are the most commonly prescribed first-line anti-hypertensive drugs in India.
G Agnes Golda Priyadarshini +4 more
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Calcium Channel Antagonist Toxicity
MedEdPORTAL, 2014 Introduction This simulation case was designed to teach emergency medicine physicians, pediatricians, and other health care providers about the clinical presentation, stabilization, and medical management of the patient with suspected or proven toxic ...
Elaine Fielder +2 more
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