The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves+3 more
core +1 more source
Calcium oscillation on homogeneous and heterogeneous networks of ryanodine receptor [PDF]
Calcium oscillation is an important calcium homeostasis, imbalance of which is the key mechanism of initiation and progression of many major diseases. The formation and maintenance of calcium homeostasis are closely related to the spatial distribution of calcium channels.
arxiv +1 more source
Calcium-Mediated Mechanisms of Cystic Expansion [PDF]
In this review, we will discuss several well-accepted signaling pathways toward calcium-mediated mechanisms of cystic expansion. The second messenger calcium ion has contributed to a vast diversity of signal transduction pathways. We will dissect calcium
Abdul-Majeed, Shakila, Nauli, Surya M.
core +2 more sources
Proximal tubule (PT) transports most of the renal Ca2+, which was usually described as paracellular (passive). We found a regulated Ca2+ entry pathway in PT cells via the apical transient receptor potential canonical 3 (TRPC3) channel, which initiates ...
Samuel Shin+5 more
doaj
The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. [PDF]
Oleamide is a sleep-inducing lipid originally isolated from the cerebrospinal fluid of sleep-deprived cats. Oleamide was found to potently and selectively inactivate gap junction-mediated communication between rat glial cells.
Cao+35 more
core +2 more sources
Interplay Between Calcium and AMPK Signaling in Human Cytomegalovirus Infection
Calcium signaling and the AMP-activated protein kinase (AMPK) signaling networks broadly regulate numerous aspects of cell biology. Human Cytomegalovirus (HCMV) infection has been found to actively manipulate the calcium-AMPK signaling axis to support ...
Diana M. Dunn, Joshua Munger
doaj +1 more source
An Age-dependent Feedback Control Model for Calcium and Reactive Oxygen Species in Yeast Cells [PDF]
Calcium and reactive oxygen species (ROS) interact with each other and play an important role in cell signaling networks. Based on the existing mathematical models, we develop an age-dependent feedback control model to simulate the interaction. The model consists of three subsystems: cytosolic calcium dynamics, ROS generation from the respiratory chain
arxiv
A zero-inflated gamma model for deconvolved calcium imaging traces [PDF]
Calcium imaging is a critical tool for measuring the activity of large neural populations. Much effort has been devoted to developing "pre-processing" tools for calcium video data, addressing the important issues of e.g., motion correction, denoising, compression, demixing, and deconvolution. However, statistical modeling of deconvolved calcium signals
arxiv +1 more source
Comparative analysis of calcium spikes upon activation of serotonin(1A) and purinergic receptors. [PDF]
Calcium signaling represents one of the most important signaling cascades in cells and regulates diverse processes such as exocytosis, muscle contraction and relaxation, gene expression and cell growth.
Roopali Saxena+2 more
doaj +1 more source
Advances and current challenges in calcium signaling.
Content Summary 414 I. Introduction 415 II. Ca2+ importer and exporter in plants 415 III. The Ca2+ decoding toolkit in plants 415 IV. Mechanisms of Ca2+ signal decoding 417 V. Immediate Ca2+ signaling in the regulation of ion transport 418 VI.
J. Kudla+8 more
semanticscholar +1 more source