Results 91 to 100 of about 29,724,597 (193)
Journal of Fish Biology, EarlyView.Abstract Wild Atlantic salmon migrate to sea following completion of a developmental process known as parr‐smolt transformation (PST), which establishes a seawater (SW) tolerant phenotype. Effective imitation of this aspect of anadromous life history is a crucial aspect of commercial salmon production, with current industry practice being marred by ...
Lars Grønvold +10 more
wiley +1 more source
Stabilization of calpain large subunits by overexpression of truncated calpain small subunit in L8 myoblasts. [PDF]
, 2010 [[abstract]]The objectives were to investigate the function of the small subunit in the calpain system by expression of the autolytic form of this subunit in L8 myoblasts.
Chung, T. C.;Liang, Y. C.;Yeh, J. Y.;Ou, B. R.
core
Animal Production: Indonesian Journal of Animal Production, 2012 . The purpose of research was to investigate whether there was influence of the addition of concentrates in basal feed on meat tenderness and calpastatin and calpain activities of three muscles of Kejobong does.
M Socheh +3 more
doaj
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Acta Neuropathologica CommunicationsPyroptosis contributes to the neuronal damage that occurs during epilepsy. Calcium-activated neutral protease (calpain) dissociates cysteinyl aspartate specific proteinase-1 (caspase-1, cas-1) from the cytoskeleton, and the activated cas-1 is responsible
Lihan Liu +8 more
doaj +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
CellsParkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra, and key pathways such as neuroinflammation, oxidative stress, and autophagy are believed to significantly contribute to the mechanisms of ...
Vandana Zaman +5 more
doaj +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Substance‐use disorders are increasingly linked to structural and functional brain alterations consistent with neuroaxonal injury. Neurofilament light chain (NfL) is a sensitive blood‐based marker of axonal damage, but evidence in substance‐using populations remains fragmented.
João Antônio Valadão Leal +2 more
wiley +1 more source
Of mice and men—The emerging oral–gut–brain axis of health and disease
Periodontology 2000, EarlyView.Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila +1 more
wiley +1 more source
Mn promoted calpain 1 mRNA and protein expression.
, 2015 After brain slices were treated with calpain inhibitor II and Mn, mRNA and protein expression of calpain 1 were measured from brain homogenates. (A) The mRNA expression levels were analyzed using a real-time qPCR assay.
Zhao-Fa Xu (700391) +5 more
core +1 more source