Results 101 to 110 of about 21,266,386 (226)

Clinical correlation of calpain-1 and glypican-3 expression with gallbladder carcinoma

Oncology Letters, 2016
Gallbladder carcinoma (GBC) possesses a poor prognosis, which is primarily attributed to the lack of early and timely surgical intervention. Calpain-1 and glypican-3 have been implicated in the progression of various types of cancer. The present study aimed to detect the expression of calpain-1 and glypican-3 in GBC, and analyzed whether the expression
LUO, WEIQING, REN, ZHIGANG, GAO, SHENG, JIN, HAILONG, ZHANG, GEER, ZHOU, LIN, ZHENG, SHUSEN   +6 more
openaire   +3 more sources

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Mn promoted calpain 1 mRNA and protein expression.

, 2015
After brain slices were treated with calpain inhibitor II and Mn, mRNA and protein expression of calpain 1 were measured from brain homogenates. (A) The mRNA expression levels were analyzed using a real-time qPCR assay.
Zhao-Fa Xu (700391), Tian-Yao Yang (700390), Bin Xu (10691), Wei Liu (20030), Yu Deng (162738), Shu Feng (391684)   +5 more
core   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Calpain inhibitor II disturbed the interaction between alpha-synuclein and calpain 1.

, 2015
Colocalization fluorescence signals of alpha-synuclein and calpain 1 on brain slices were examined with an Olympus confocal microscope using the 40× objective lens. (A) Confocal microscopy images of immunofluorescence staining for C-terminal fragments of
Zhao-Fa Xu (700391), Tian-Yao Yang (700390), Bin Xu (10691), Wei Liu (20030), Yu Deng (162738), Shu Feng (391684)   +5 more
core   +1 more source

Tenderness and the Calpain System of Three Different Types of Muscles of Kejobong Does under Two Different Energy Levels

Animal Production: Indonesian Journal of Animal Production, 2012
. The purpose of research was to investigate whether there was influence of the addition of concentrates in basal feed on meat tenderness and calpastatin and calpain activities of three muscles of Kejobong does.
M Socheh, Ismaya Ismaya, I Gede Suparta Budisatria, Kustantinah Kustantinah   +3 more
doaj  

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitric oxide synthase expression and reducing apoptosis

Asian Journal of Andrology, 2018
Calpain activation contributes to hyperglycemia-induced endothelial dysfunction and apoptosis. This study was designed to investigate the role of calpain inhibition in improving diabetic erectile dysfunction (ED) in mice. Thirty-eight-week-old male C57BL/
Hao Li, Li-Ping Chen, Tao Wang, Shao-Gang Wang, Ji-Hong Liu   +4 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source