Disruption of Endoplasmic Reticulum and ROS Production in Human Ovarian Cancer by Campesterol [PDF]
Phytosterols, which are present in a variety of foods, exhibit various physiological functions and do not have any side effects. Here, we attempted to identify functional role of campesterol in regulation of oxidative stress by leading to cell death of ...
Hyocheol Bae +4 more
doaj +4 more sources
Engineering Yarrowia lipolytica for Campesterol Overproduction. [PDF]
Campesterol is an important precursor for many sterol drugs, e.g. progesterone and hydrocortisone. In order to produce campesterol in Yarrowia lipolytica, C-22 desaturase encoding gene ERG5 was disrupted and the heterologous 7-dehydrocholesterol ...
Hao-Xing Du +6 more
doaj +5 more sources
Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects
Background: Increased cholesterol absorption and reduced synthesis are processes that have been associated with cardiovascular disease risk in a controversial way.
V. Nunes +9 more
semanticscholar +3 more sources
Phytosterols obtained from medicinal plants are well known for their anti-diabetic, anti-cardiovascular, anti-cancer, and anti-microbial properties. Strychnos innocua (a member of the Loganiaceae family) grows in several African nations and is frequently used for medicinal purposes.The chromatographic separation of S.
A. Uttu +3 more
semanticscholar +4 more sources
Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach. [PDF]
Steroidal 5α-reductase type 2 (S5αR2) is a key enzyme involved in the conversion of testosterone (TST) to dihydrotestosterone (DHT), a crucial process in the development of benign prostatic hyperplasia (BPH).
Buț MG +4 more
europepmc +2 more sources
Ajuga Δ24-Sterol Reductase Catalyzes the Direct Reductive Conversion of 24-Methylenecholesterol to Campesterol* [PDF]
Dimunito/Dwarf1 (DWF1) is an oxidoreductase enzyme that is responsible for the conversion of C28- and C29-Δ24(28)-olefinic sterols to 24-methyl- and 24-ethylcholesterols. Generally, the reaction proceeds in two steps via the Δ24(25) intermediate. In this
Y. Tsukagoshi +5 more
semanticscholar +3 more sources
Oxidation of β-sitosterol and campesterol in sunflower oil upon deep- and pan-frying of French fries [PDF]
Fried foods, both deep-fried and pan-fried, are enjoyed by people worldwide. Frying is one of the main factors leading to formation of phytosterols (PS) oxidation products (POP) in vegetable oils. The aim of this study was to measure the oxidation of β-sitosterol (24α-ethyl-5-cholesten-3β-ol) and campesterol (24α-methyl-5-cholesten-3β-ol) in commercial
M. Ramadan
semanticscholar +3 more sources
Phytosterols: From Preclinical Evidence to Potential Clinical Applications
Phytosterols (PSs) are plant-originated steroids. Over 250 PSs have been isolated, and each plant species contains a characteristic phytosterol composition.
Bahare Salehi +18 more
doaj +1 more source
Phytoremediation is gaining interest in recent years as it is a simple and effective strategy for heavy metal decontamination. The most straightforward strategy for successful heavy metal clean-up is searching for efficient hyperaccumulator species that ...
Ekta Bhattacharya, Suparna Mandal Biswas
doaj +1 more source
Rheumatoid Arthritis (RA) is a persistent inflammatory and autoimmune affliction, which results in significant impairment of mobility and a decline in the overall standard of living.
Sarwat Nazir +5 more
semanticscholar +1 more source

