Results 11 to 20 of about 7,967 (170)

Integrative Metabolomics and Systems Pharmacology Reveal PPARγ-Centered Antidiabetic Mechanisms of Caulerpa racemosa and Its Bioactive Compounds [PDF]

Marine Drugs
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder requiring safe, multitarget therapeutic strategies. Marine macroalgae represent an underexplored source of bioactives with pleiotropic metabolic effects.
Fahrul Nurkolis, Annette d’Arqom, Evhy Apryani, Nurmawati Fatimah, Adha Fauzi Hendrawan, Izza Afkarina, Reggie Surya, Happy Kurnia Permatasari, Dante Saksono Harbuwono, Nurpudji Astuti Taslim, Arifa Mustika, Raymond Rubianto Tjandrawinata   +11 more
doaj   +2 more sources

Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β-Hydroxycholesterol in Osteoporosis. [PDF]

Lipids
ABSTRACT Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue. Lipid metabolism disorders may contribute to osteoporosis in postmenopausal women. Phytosterols and oxysterols (OC) are involved in lipid metabolism.
He W, Eguchi S, Wang S, Tanaka Y, Sato M.   +4 more
europepmc   +3 more sources

Temperature‐Assisted Crystallization of Mustard Oil for Erucic Acid Reduction and Its Impact on Phenolic Compounds, Sterols and Oxidative Quality of Oil During Ambient Storage [PDF]

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Erucic acid (EA) content of mustard oil (MO) was decreased to < 2% level using temperature‐assisted crystallization with no effect on free fatty acids (FFAs), peroxide value (PV), and color of MO and its olein and stearin variant. Olein was rich in phenolic compounds and had higher antioxidant capacity than MO and stearin.
Muhammad Abdul Rahim, Muhammad Nadeem, Mohamed Fawzy Ramadan, Eliasse Zongo, Layla A. Alahmari   +4 more
wiley   +2 more sources

Extraction of Phospholipids From Crude Rapeseed Oil by n‐Hexane/Alcohol System: Effects of Solvent Composition on Extraction Performance and Oil Quality [PDF]

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Integrated analysis of extraction performance, phospholipid composition, oil quality, and multivariate relationships in green phospholipid recovery from crude rapeseed oil. ABSTRACT Rapeseed oil contains endogenous phospholipids (PLs) and other minor bioactive components, but conventional PL extraction methods commonly rely on chloroform‐based solvent ...
Fangcheng Shao, Jun Jin, Yihang Zhang, Lulu Yang, Xiuzhu Yu, Siyu Zhang   +5 more
wiley   +2 more sources

Campesterol induces apoptosis and inhibits proliferation in HepG2 liver cancer cells. [PDF]

Clin Exp Hepatol
Altaf A, Maqbool T, Hassan A, Nasreen GE, Summan MG, Tahir A, Iqbal U, Mirdad DS, Alharbi E, Noorwali H, Mousa AA, Jastaniah Z, Koser N.   +12 more
europepmc   +2 more sources

Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects

International Journal of Molecular Sciences, 2022
Background: Increased cholesterol absorption and reduced synthesis are processes that have been associated with cardiovascular disease risk in a controversial way. However, most of the studies involving markers of cholesterol synthesis and absorption include conditions, such as obesity, diabetes, dyslipidemia, which can be confounding factors.
Valéria Sutti Nunes, Edite Vieira Silva de Campos, Jamal Baracat, Victor França, Érica Ivana Lázaro Gomes, Raissa Peres Coelho, Edna Regina Nakandakare, Vanessa Helena Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão   +9 more
openaire   +2 more sources

Plasma cholesterol homeostasis, HDL remodeling and function during the acute phase reaction[S]

Journal of Lipid Research, 2017
Acute phase reaction (APR) is a systemic inflammation triggered by several conditions associated with lipid profile alterations. We evaluated whether APR also associates with changes in cholesterol synthesis and absorption, HDL structure, composition ...
Francesca Zimetti, Stefano De Vuono, Monica Gomaraschi, Maria Pia Adorni, Elda Favari, Nicoletta Ronda, Maria Anastasia Ricci, Fabrizio Veglia, Laura Calabresi, Graziana Lupattelli   +9 more
doaj   +1 more source

Phytosterol ester processing in the small intestine: impact on cholesterol availability for absorption and chylomicron cholesterol incorporation in healthy humans[S]

Journal of Lipid Research, 2011
Phytosterols (plant sterols and stanols) can lower intestinal cholesterol absorption, but the complex dynamics of the lipid digestion process in the presence of phytosterol esters (PEs) are not fully understood.
Marie Josèphe Amiot, Diny Knol, Nicolas Cardinault, Marion Nowicki, Romain Bott, Claudine Antona, Patrick Borel, Jean-Paul Bernard, Guus Duchateau, Denis Lairon   +9 more
doaj   +1 more source

Could Lowering Phytosterol Absorption as Part of Lipid-Lowering Therapy Have a Beneficial Effect on Residual Risk?

Metabolites, 2023
Plant sterols are molecules that are structurally similar to cholesterol and provided only as dietary sources (e.g., vegetables, fruits, nuts, cereals) since they cannot be synthesized by humans.
Panagiotis Anagnostis, Vasileios Kotsis, Maciej Banach, Dimitri P. Mikhailidis   +3 more
doaj   +1 more source

Efficiency of intestinal cholesterol absorption in humans is not related to apoE phenotype

Journal of Lipid Research, 2003
The present study investigated the role of apolipoprotein E (apoE) phenotype on intestinal cholesterol absorption and cholesterol synthesis. Studies were carried out in eight subjects homozygous for the apoE4 and 12 subjects homozygous for the E2 allele (
Klaus von Bergmann, Dieter Lütjohann, Bernhard Lindenthal, Armin Steinmetz   +3 more
doaj   +1 more source