Results 161 to 170 of about 10,355 (205)

Increased campesterol synthesis by improving lipid content in engineered Yarrowia lipolytica

Applied Microbiology and Biotechnology, 2020
Sterols attract increasing attention due to their important bioactivities. The oleaginous yeast Yarrowia lipolytica has large lipid droplets, which provide storage for the accumulated steroid compounds. In this study, we have successfully constructed a campesterol biosynthetic pathway by modifying the synthetic pathway of ergosterol in Y.
Ching Yuan Hu, Yong Hong Meng, Yonghong Meng   +2 more
exaly   +3 more sources

Plasma Lathosterol and Campesterol in Detection of Ileal Dysfunction

Scandinavian Journal of Gastroenterology, 1988
Plasma lathosterol levels reflect cholesterol synthesis, especially that induced by bile acid malabsorption, whereas plasma plant sterol contents change in parallel with cholesterol and fat absorption. The significance of lathosterols and plant sterols (campesterol and sitosterol) was therefore studied in detection of ileal dysfunction in 29 patients ...
M A Färkkilä, T A Miettinen
exaly   +3 more sources

Improved campesterol production in engineered Yarrowia lipolytica strains

Biotechnology Letters, 2017
To engineer Yarrowia lipolytica for improving the heterologous production of campesterol (a key precursor to manufacture pharmaceutical steroids).By screening 7-dehydrocholesterol reductase (DHCR7) from diverse species, DHCR7 from Danio rerio was the best candidate for campesterol synthesis.
Wenhai Xiao, Mingdong Yao, Ying-Jin Yuan
exaly   +3 more sources

Oxidation of sitosterol and campesterol in foods upon cooking with liquid margarines without and with added plant sterol esters

Food Chemistry, 2018
Plant sterol (PS) oxidation products (POP) derived from sitosterol and campesterol were measured in 15 foods cooked with liquid margarine without (control) and with added 7.5% PS. POP were analyzed using a GC-MS method. PS liquid vs.
Hans-Gerd Janssen, Elke A Trautwein, Diny Knol   +2 more
exaly   +2 more sources

Uptake of campesterol in pigeon intestine

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1971
Abstract Campesterol was the major plant sterol found in the gastrointestinal tract, liver, and plasma of pigeons fed diets containing large amounts of β-sitosterol and small amounts of campesterol. On feeding plant sterol mixtures, it was found that campesterol was taken up preferentially by the pigeon intestine.
M T, Subbiah, B A, Kottke, I A, Carlo
openaire   +2 more sources

Uroprotective Potential of Campesterol in Cyclophosphamide Induced Interstitial Cystitis; Molecular Docking Studies

Chemistry and Biodiversity, 2023
AbstractCyclophosphamide (CYP) is commonly used to treat cancer of the ovaries, breast, lymph, and blood system and produces interstitial cystitis (IC) via its urotoxic metabolite: i. e., acrolein. The present study was aimed to investigate the uroprotective effect of campesterol (a steroidal phytochemical) in cyclophosphamide induced IC.
Irfan Anjum, Shah Jahan, Saima Najm
exaly   +3 more sources

Mechanism of campesterol demethylation in insect

Tetrahedron Letters, 1982
Abstract [24- 2 H]-, [25- 2 H]-, and [23,23,25- 2 H 3 ]-24ξ-methylcholesterol as well as [23,23,25- 2 H 3 ]-24-methylenecholesterol were metabolized in the silkworm Bombyx mori to cholesterol containing zero, one, three and three deuterim, respectively.
S. Maruyama, Y. Fujimoto, M. Morisaki, N. Ikekawa   +3 more
openaire   +1 more source

Identification of β‐sitosterol, campesterol, and stigmasterol in human serum

Lipids, 1975
AbstractThe presence of 3 plant sterols, β‐sitosterol, campesterol, and stigmasterol, has been demonstrated in the serum from 2 patients with β‐sitosterolemia and xanthomatosis.
M K, Rao, E G, Perkins, W E, Connor, A K, Bhattacharyya   +3 more
openaire   +2 more sources

ChemInform Abstract: MECHANISM OF CAMPESTEROL DEMETHYLATION IN INSECT

Chemischer Informationsdienst, 1982
AbstractZur Aufklärung des Reaktionsmechanismus der Demethylierungsreaktion der im Titel genannten Verbindung (I) durch Phytophageninsekten werden nach bekannten Verfahren deuterierte Cholesterinderivate (II) hergestellt, und ihre Metabolitenbildung im Seidenwurm Bombyx mori wird untersucht.
S. MARUYAMA, Y. FUJIMOTO, M. MORISAKI, N. IKEKAWA   +3 more
openaire   +1 more source

Purification of campesterol and preparation of 7‐dehydrocampesterol, 7‐campestenol and campestanol

Lipids, 1974
AbstractCampesterol ([24R]‐24‐methyl‐5‐cholesten‐3β‐ol) was isolated from a soybean sterol mixture and purified on a small scale by column chromatography and on a large scale by crystallization from acetone to 97% purity. From this, 7‐dehydrocampesterol ([24R]‐24‐methyl‐5,7‐cholestadien‐3β‐ol) and campestanol ([24R]‐24‐methyl‐cholestan‐3β‐ol) were ...
H W, Kircher, F U, Rosenstein
openaire   +2 more sources