Results 11 to 20 of about 11,333,085 (312)
Fibroblast growth factor receptors in breast cancer
Tumor Biology, 2017 Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer.
Shuwei Wang, Zhongyang Ding
doaj +2 more sources
Cancer-associated fibroblasts in cholangiocarcinoma [PDF]
Current Opinion in Gastroenterology, 2020 Purpose of review To give a state-of-art knowledge regarding cancer-associated fibroblasts (CAF) in cholangiocarcinoma (CCA) based both on direct evidence and studies on other desmoplastic cancers. High contingency of CAF characterizes CCA, a tumor with a biliary epithelial phenotype that can emerge anywhere in the biliary tree.
Vaquero, Javier +2 more
openaire +3 more sources
Biomarkers for cancer-associated fibroblasts [PDF]
Biomarker Research, 2020 Abstract Cancer-associated fibroblasts (CAFs) are the key component of tumor stromal. High heterogeneity of CAFs reflects in their origin, phenotype and function. Biological function which can be suggested by biomarkers of distinct CAF subgroups may be different, even opposite, just like water and fire.
Chencheng Han, Tongyan Liu, Rong Yin
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Profiling Cancer-Associated Fibroblasts in Melanoma [PDF]
International Journal of Molecular Sciences, 2021 Solid tumors are complex systems characterized by dynamic interactions between neoplastic cells, non-tumoral cells, and extracellular components. Among all the stromal cells that populate tumor microenvironment, fibroblasts are the most abundant elements and are critically involved in disease progression.
Federica Papaccio +6 more
openaire +2 more sources
Green Curmin Reduces Pro-inflammatory Cytokines and Fibroblast-Associated Colon Cancer Migration [PDF]
Pharmaceutical Sciences, 2021 Background: Green Curmin is a soluble curcumin extract product made in Thailand that has been reported to reduce gastric inflammation. Inflammatory cytokines including IL-1α, IL-6,and TNF-β play a crucial role in cancer cell migration, which is a major ...
Nasapon Povichit +3 more
doaj +1 more source
On the origin of cancer-associated fibroblasts [PDF]
Cell Cycle, 2009 of the origin of CAFs in mouse tumors is that only a portion of the CAFs was found to be of a single origin, suggesting that all CAFs are not derived from the same source, but rather originate from several different supplies. Evidence from human tumors is scarce regarding the source(s) from which CAFs are recruited.We recently identified a role for ...
Charlotte, Anderberg, Kristian, Pietras
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Promotion of Cholangiocarcinoma Growth by Diverse Cancer-associated Fibroblast Subpopulations
, 2021 Raw data for western blots and phosphoarrays in figure 7 and supplementary figure 7 of our study: Affo et al. "Promotion of Cholangiocarcinoma Growth by Diverse Cancer-associated Fibroblast Subpopulations".
Affo, S (via Mendeley Data)
core +2 more sources
MicroRNA‐200c overexpression in cancer‐associated fibroblasts decreases interleukin‐2 secretion
Clinical and Translational Discovery, 2022 miR‐200c‐3p is demonstrated to play the role of tumour suppressor in different tumours. However, the miR‐200c‐3p biological function in normal fibroblast (NF) and cancer‐associated fibroblast (CAF) remains unclear.
Laleh Shariati +5 more
doaj +1 more source
The application of FAPI-targeted theranostics in pancreatic cancer: a narrative review
Journal of Pancreatology, 2022 Pancreatic cancer is one of the most lethal malignancies in the world. Cancer-associated fibroblasts are one of the main components of tumor microenvironment in pancreatic cancer and play an essential role in tumor progression.
Meixi Liu +3 more
doaj +1 more source
SnapShot: Cancer-Associated Fibroblasts
Cell, 2020 Cancer-associated fibroblasts (CAFs) are an integral component of the tumor microenvironment and have both tumor-promoting and tumor-suppressive functions. This SnapShot summarizes the origins of CAFs, their diverse functions, and how this relates to heterogeneity within the population.
Danielle, Park +2 more
openaire +2 more sources