Results 31 to 40 of about 11,333,085 (312)
MicroRNA regulation in cancer-associated fibroblasts [PDF]
Cancer Immunology, Immunotherapy, 2011 The microenvironment of cancer cells has proven to be a critical component of tumors that strongly influences cancer development and progression into invasive and metastatic disease. Compared to normal tissue, dramatic differences in gene expression occur in multiple cell types that constitute the tumor microenvironment including cancer-associated ...
Olga, Aprelikova, Jeffrey E, Green
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Tumor Biology, 2017 Ovarian cancer is the most lethal gynecologic malignancy, due to its high propensity for metastasis. Cancer-associated fibroblasts, as the dominant component of tumor microenvironment, are crucial for tumor progression. However, the mechanisms underlying
Yuanzhen Sun +5 more
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Redox Report, 2023 Objective: Obstructive sleep apnea (OSA) is associated with severity of pneumonia; however, the mechanism by which OSA promotes lung cancer progression is unclear.Methods: Twenty-five lung cancer patients were recruited to investigate the relationship ...
Zhilei Cui +11 more
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Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in the dendritic cell-based vaccine [PDF]
, 2015 雑誌掲載時のタイトル: Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine博士（医学 ...
Ohshio, Yasuhiko +8 more
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Biomolecules, 2022 The continuous remodeling of the tumor microenvironment (TME) during prostate tumorigenesis is emerging as a critical event that facilitates cancer growth, progression and drug-resistance.
Jasmine S. Owen +2 more
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Diversity and Biology of Cancer-Associated Fibroblasts
Physiological Reviews, 2021 Efforts to develop anti-cancer therapies have largely focused on targeting the epithelial compartment, despite the presence of non-neoplastic stromal components that substantially contribute to the progression of the tumor. Indeed, cancer cell survival, growth, migration, and even dormancy are influenced by the surrounding tumor microenvironment (TME).
Giulia Biffi, David A. Tuveson
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FSP-1 expression in cancer cells is relevant to long-term oncological outcomes in nonmetastatic colorectal cancer [PDF]
Korean Journal of Clinical Oncology, 2022 Purpose Recent studies have revealed that the expression of cancer-associated fibroblast (CAF) activation biomarkers in cancer cells is associated with clinical outcomes in patients with certain types of malignant tumors.
Sun Bin Im +6 more
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Cancer associated fibroblasts phenotypic and functional heterogeneity [PDF]
Frontiers in Bioscience, 2020 Cancer associated fibroblasts (CAFs) are the most abundant stromal cell-type in solid tumor-microenvironment (TME) and have emerged as key player in tumor progression. CAFs establish communication with cancer cells through paracrine mechanisms or via direct cell adhesion as well as influence the cancer cell behaviour indirectly by remodelling the ...
Ankit Kumar Patel, Sandeep Singh
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Frontiers in Oncology, 2022 Pancreatic cancer is a lethal malignancy with a 5-year survival rate of about 10% in the United States, and it is becoming an increasingly prominent cause of cancer death. Among pancreatic cancer patients, pancreatic ductal adenocarcinoma (PDAC) accounts
Jinbao Zhang +3 more
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Cancer-associated fibroblasts in acute leukemia
Frontiers in Oncology, 2022 Although the prognosis for acute leukemia has greatly improved, treatment of relapsed/refractory acute leukemia (R/R AL) remains challenging. Recently, increasing evidence indicates that the bone marrow microenvironment (BMM) plays a crucial role in leukemogenesis and therapeutic resistance; therefore, BMM-targeted strategies should be a potent ...
Ling Gu +9 more
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