Results 81 to 90 of about 11,333,085 (312)

Supplementary Figure S4 from Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer

, 2022
Supplementary Figure S4 from Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck ...
Sohini Roy (743212), Diana Graves (15045846), Kamran Idrees (14974134), Michael Gibson (15045858), Aleksandar Obradovic (7549517), Paula Hurley (10941824), X. Shirley Liu (14931254), Michael Korrer (15045849), Abdullah Naveed (15045855), Peng Jiang (14956410), Andrea Califano (15018354), Yu Wang (15045852), Joseph Curry (7890260), Young J. Kim (15040152), Ravindra Uppaluri (6957617), Adam Luginbuhl (9229314), Charles G. Drake (7549529), Yaomin Xu (221417)   +17 more
core   +1 more source

Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts [PDF]

BioMed Research International, 2017
The current study is to develop a gentle and efficient method for purification of fibroblast-activation protein positive (FAP+) cancer-associated fibroblasts (CAFs) from tumor tissues. Fresh tissues were isolated from BALB/c-Nude mice bearing human liver cancer cell line (HepG2), fully minced and separated into three parts, and digested with trypsin ...
Yingying Huang, Sufang Zhou, Yong Huang, Duo Zheng, Qiqi Mao, Jian He, Yiwei Wang, Dabing Xue, Xiaoling Lu, Nuo Yang, Yongxiang Zhao   +10 more
openaire   +2 more sources

Exploring the diversity of cancer-associated fibroblasts: insights into mechanisms of drug resistance

Frontiers in Cell and Developmental Biology
Introduction: Among the various stromal cell types within the tumor microenvironment, cancer-associated fibroblasts (CAFs) emerge as the predominant constituent, exhibiting a diverse array of oncogenic functions not intrinsic to normal fibroblasts. Their
Anastasia N. Kazakova, Anastasia N. Kazakova, Anastasia N. Kazakova, Maria M. Lukina, Maria M. Lukina, Maria M. Lukina, Ksenia S. Anufrieva, Irina V. Bekbaeva, Irina V. Bekbaeva, Olga M. Ivanova, Olga M. Ivanova, Olga M. Ivanova, Polina V. Shnaider, Polina V. Shnaider, Polina V. Shnaider, Andrey Slonov, Georgij P. Arapidi, Georgij P. Arapidi, Georgij P. Arapidi, Georgij P. Arapidi, Victoria O. Shender, Victoria O. Shender, Victoria O. Shender   +22 more
doaj   +1 more source

Prognostic role of fibroblast growth factor receptor 2 in human solid tumors: A systematic review and meta-analysis

Tumor Biology, 2017
In the past decades, the oncogenic role of fibroblast growth factor receptor 2 has been demonstrated in a number of cancer types. However, studies have reported contradictory findings concerning the correlation between fibroblast growth factor receptor 2
Gang Liu, Disheng Xiong, Rui Xiao, Zhengjie Huang   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Vinay Varadan, Hoon Kim, John Watkinson, Dimitris Anastassiou   +3 more
core  

Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells

, 2019
Western blot analysis of phosphorylated-Akt (Ser473) and phosphorylated-Erk in endometrial cancer cells ECC-1, after treatment with the secretion of normal endometrial fibroblast (T-HESC) or cancer-associated fibroblasts (EC6-Fib, EC7-Fib, EC11-Fib and ...
Ivy Chung (7370150), Zahurin Mohamed (386148), Noor Azmi Mat Adenan (7478283), Seng Tian Tham (7478281), Kavita S. Subramaniam (438295), Woo Yin Ling (7148069)   +5 more
core   +1 more source

Supplementary Table S2 from Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer

, 2022
Supplementary Table S2 from Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck ...
Sohini Roy (743212), Diana Graves (15045846), Kamran Idrees (14974134), Michael Gibson (15045858), Aleksandar Obradovic (7549517), Paula Hurley (10941824), X. Shirley Liu (14931254), Michael Korrer (15045849), Abdullah Naveed (15045855), Peng Jiang (14956410), Andrea Califano (15018354), Yu Wang (15045852), Joseph Curry (7890260), Young J. Kim (15040152), Ravindra Uppaluri (6957617), Adam Luginbuhl (9229314), Charles G. Drake (7549529), Yaomin Xu (221417)   +17 more
core   +1 more source

Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer

Breast Cancer Research
Background Human breast cancer most frequently originates within a well-defined anatomical structure referred to as the terminal duct lobular unit (TDLU).
Mikkel Morsing Bagger, Jonas Sjölund, Jiyoung Kim, Katharina Theresa Kohler, René Villadsen, Abbas Jafari, Moustapha Kassem, Kristian Pietras, Lone Rønnov-Jessen, Ole William Petersen   +9 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source