Results 191 to 200 of about 298,386 (364)

Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors

open access: yesMolecular Therapy: Methods & Clinical Development, 2019
H. Büning, A. Srivastava
semanticscholar   +1 more source

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

open access: yesSmall, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi   +11 more
wiley   +1 more source

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

open access: yesSmall, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt   +7 more
wiley   +1 more source

A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

open access: yesNature Medicine, 2019
S. Yant   +29 more
semanticscholar   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos   +3 more
wiley   +1 more source

Selective autophagy limits cauliflower mosaic virus infection by NBR1-mediated targeting of viral capsid protein and particles

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
A. Hafrén   +5 more
semanticscholar   +1 more source

Scattering from `Babinet' particles (or not…): spherical particles made up of spheres and spherical particles with spherical voids

open access: yesJournal of Applied Crystallography, EarlyView.
Small‐angle scattering form factors of composite particles built from either embedded spheres or randomly distributed voids within a sphere are obtained by Monte Carlo simulations, and analytical expressions that reproduce the simulations are derived.The small‐angle scattering form factors of two classes of composite particles with contrasting internal
Jan Skov Pedersen   +2 more
wiley   +1 more source

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