Results 191 to 200 of about 174,454 (241)

Current perspectives on alphavirus encapsidation, assembly and budding. [PDF]

Front Cell Infect Microbiol
Bhardwaj K, Ranjith-Kumar CT, Guchhait P, Vrati S.   +3 more
europepmc   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Research note: the putative nuclear localization signal of duck circovirus type 1 cap protein is critical for VLP assembly. [PDF]

Poult Sci
Lei X, Wei P, Wang D, Jiang Y, Yu W, Wang A, Wu Z, Zhu S.   +7 more
europepmc   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

Water microdroplet platforms for sustainable, reagent-free viral disinfection. [PDF]

J Biol Eng
Sheen J, Lee J, Kim Y, Lee K, Lee JK.
europepmc   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, Volume 2, Issue 1, Page 106-129, March 2026.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Calicivirus assembly and stability are mediated by the N-terminal domain of the capsid protein with the involvement of the viral genome. [PDF]

PLoS Pathog
Novoa G, Mata CP, Mertens J, Zamora-Ceballos M, Martínez-Romero JM, Fontana J, Carrascosa JL, Bárcena J, Castón JR.   +8 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Synthesizing selection mosaic theory and host-pathogen theory to explain large-scale pathogen coexistence. [PDF]

Nat Commun
Dixon KP, Koval WT, Polivka CM, Bird G, Dukic V, Dwyer G.   +5 more
europepmc   +1 more source