Flavivirus Capsid Proteins Inhibit the Interferon Response [PDF]
Viruses, 2022 Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular
Adriana M. Airo +9 more
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Atlas of Interactions Between Decoration Proteins and Major Capsid Proteins of Coliphage N4 [PDF]
VirusesColiphage N4 is a representative species of the Schitoviridae family of bacteriophages. Originally structurally studied in 2008, the capsid structure was solved to 14 Å to reveal an interesting arrangement of Ig-like decoration proteins across the ...
Klem McJarrow-Keller +5 more
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Viral capsid proteins are segregated in structural fold space.
PLoS Computational Biology, 2013 Viral capsid proteins assemble into large, symmetrical architectures that are not found in complexes formed by their cellular counterparts. Given the prevalence of the signature jelly-roll topology in viral capsid proteins, we are interested in whether ...
Shanshan Cheng, Charles L Brooks
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Plant virus movement proteins originated from jelly-roll capsid proteins. [PDF]
PLoS Biology, 2023 Numerous, diverse plant viruses encode movement proteins (MPs) that aid the virus movement through plasmodesmata, the plant intercellular channels. MPs are essential for virus spread and propagation in distal tissues, and several unrelated MPs have been ...
Anamarija Butkovic +3 more
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Divergent Effects of Circoviridae Capsid Proteins on Type I Interferon Signaling [PDF]
PathogensViruses in the Circoviridae family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome ...
Anon H. Kosaka +7 more
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Capsid protein structure in Zika virus reveals the flavivirus assembly process
Nature Communications, 2020 The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle,
Ter Yong Tan +11 more
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Role of capsid proteins in parvoviruses infection [PDF]
Virology Journal, 2015 The parvoviruses are widely spread in many species and are among the smallest DNA animal viruses. The parvovirus is composed of a single strand molecule of DNA wrapped into an icosahedral capsid. In a viral infection, the massy capsid participates in the
M. Tu +4 more
semanticscholar +3 more sources
Capsid-incorporation of antigens into adenovirus capsid proteins for a vaccine approach. [PDF]
Molecular Pharmaceutics, 2011 Some viral vectors are potent inducers of cellular and humoral responses; therefore, viral vectors can be used to vaccinate against cancer or infectious diseases. This report will focus on adenovirus (Ad)-based vectors. Traditional viral-vector vaccination embodies the concept that the vector uses the host-cell machinery to express antigens that are ...
Q. Matthews
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Interaction of Poliovirus Capsid Proteins with the Cellular Autophagy Pathway [PDF]
Viruses, 2021 The capsid precursor P1 constitutes the N-terminal part of the enterovirus polyprotein. It is processed into VP0, VP3, and VP1 by the viral proteases, and VP0 is cleaved autocatalytically into VP4 and VP2. We observed that poliovirus VP0 is recognized by
Anna Zimina +4 more
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Characterizing Glycosylation of Adeno-Associated Virus Serotype 9 Capsid Proteins Generated from HEK293 Cells through Glycopeptide Mapping and Released Glycan Analysis [PDF]
MicroorganismsRecombinant adeno-associated viral (AAV) vectors have emerged as prominent gene delivery vehicles for gene therapy. AAV capsid proteins determine tissue specificity and immunogenicity and play important roles in receptor binding, the escape of the virus ...
Yu Zhou, Sonal Priya, Joseph Y. Ong
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