Results 1 to 10 of about 5,586,089 (360)
Capsid Proteins Are Necessary for Replication of a Parvovirus. [PDF]
J Virol, 2021 AbstractDespite tight genetic compression, viral genomes are often organized in functional gene clusters, a modular structure that might favor their evolvability. This has greatly facilitated biotechnological developments, such as the recombinant Adeno-Associated Virus (AAV) systems for gene therapy.
Labadie T +4 more
europepmc +11 more sources
Atlas of Interactions Between Decoration Proteins and Major Capsid Proteins of Coliphage N4. [PDF]
VirusesColiphage N4 is a representative species of the Schitoviridae family of bacteriophages. Originally structurally studied in 2008, the capsid structure was solved to 14 Å to reveal an interesting arrangement of Ig-like decoration proteins across the ...
McJarrow-Keller K +5 more
europepmc +2 more sources
Flavivirus Capsid Proteins Inhibit the Interferon Response. [PDF]
Viruses, 2022 Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular
Airo AM +9 more
europepmc +2 more sources
Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission. [PDF]
Cells, 2021 Vector transmission of plant viruses is basically of two types that depend on the virus helper component proteins or the capsid proteins. A number of plant viruses belonging to disparate groups have developed unusual capsid proteins providing for ...
Agranovsky A.
europepmc +2 more sources
Divergent Effects of <i>Circoviridae</i> Capsid Proteins on Type I Interferon Signaling. [PDF]
PathogensViruses in the Circoviridae family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome ...
Kosaka AH +7 more
europepmc +2 more sources
Plant virus movement proteins originated from jelly-roll capsid proteins. [PDF]
PLoS Biol, 2023 Numerous, diverse plant viruses encode movement proteins (MPs) that aid the virus movement through plasmodesmata, the plant intercellular channels. MPs are essential for virus spread and propagation in distal tissues, and several unrelated MPs have been ...
Butkovic A +3 more
europepmc +2 more sources
Characterizing Glycosylation of Adeno-Associated Virus Serotype 9 Capsid Proteins Generated from HEK293 Cells through Glycopeptide Mapping and Released Glycan Analysis. [PDF]
MicroorganismsRecombinant adeno-associated viral (AAV) vectors have emerged as prominent gene delivery vehicles for gene therapy. AAV capsid proteins determine tissue specificity and immunogenicity and play important roles in receptor binding, the escape of the virus ...
Zhou Y, Priya S, Ong JY.
europepmc +2 more sources
Interaction of Poliovirus Capsid Proteins with the Cellular Autophagy Pathway. [PDF]
Viruses, 2021 The capsid precursor P1 constitutes the N-terminal part of the enterovirus polyprotein. It is processed into VP0, VP3, and VP1 by the viral proteases, and VP0 is cleaved autocatalytically into VP4 and VP2. We observed that poliovirus VP0 is recognized by
Zimina A +4 more
europepmc +2 more sources
Viruses, 2021 Penetration of the viral genome into a host cell nucleus is critical for initiation of viral replication for most DNA viruses and a few RNA viruses. For herpesviruses, viral DNA ejection into a nucleus occurs when the capsid docks at the nuclear pore ...
José Ramon Villanueva-Valencia +2 more
doaj +1 more source
Arthritogenic Alphavirus Capsid Protein
Life, 2021 In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly.
Rao, Shambhavi, Taylor, Adam
openaire +4 more sources