Results 31 to 40 of about 145,423 (282)
Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
Nature Communications, 2023 Singapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a highly pathogenic iridovirid. SGIV infection results in massive economic losses to the aquaculture industry and significantly threatens global biodiversity. In recent
Zhennan Zhao +14 more
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Rotavirus Capsid Protein VP5* Permeabilizes Membranes [PDF]
Journal of Virology, 1999 ABSTRACT Proteolytic cleavage of the VP4 outer capsid spike protein into VP8* and VP5* proteins is required for rotavirus infectivity and for rotavirus-induced membrane permeability. In this study we addressed the function of the VP5* cleavage fragment in permeabilizing membranes.
E, Denisova +6 more
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Neck and capsid architecture of the robust Agrobacterium phage Milano
Communications Biology, 2023 Large gaps exist in our understanding of how bacteriophages, the most abundant biological entities on Earth, assemble and function. The structure of the “neck” region, where the DNA-filled capsid is connected to the host-recognizing tail remains poorly ...
Ravi R. Sonani +9 more
doaj +1 more source
Viruses, 2014 To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment.
Eva Bilkova +2 more
doaj +1 more source
Iodination of Poliovirus Capsid Proteins
Journal of General Virology, 1977 Summary Iodination of the surface of poliovirus and its artificial empty capsid demonstrated predominant labelling of polypeptide VP 1 on the intact particle and an increased labelling of polypeptide VP 2 on the artificial empty capsid.
T W, Beneke +3 more
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Scientific Reports, 2022 Marseilleviridae is a family of giant viruses, showing a characteristic internal membrane with extrusions underneath the icosahedral vertices. However, such large objects, with a maximum diameter of 250 nm are technically difficult to examine at sub ...
Akane Chihara +6 more
doaj +1 more source
Multifaceted Capsid Proteins: Multiple Interactions Suggest Multiple Roles for Pepino mosaic virus Capsid Protein [PDF]
Molecular Plant-Microbe Interactions®, 2014 Pepino mosaic virus (PepMV) (family Alphaflexiviridae, genus Potexvirus) is a mechanically transmitted tomato pathogen that, over the last decade, has evolved from emerging to endemic worldwide. Here, two heat-shock cognate (Hsc70) isoforms were identified as part of the coat protein (CP)/Hsc70 complex in vivo, following full-length PepMV and CP ...
Matthaios M. Mathioudakis +4 more
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Visualizing HIV-1 Capsid and Its Interactions with Antivirals and Host Factors
Viruses, 2021 Understanding of the construction and function of the HIV capsid has advanced considerably in the last decade. This is due in large part to the development of more sophisticated structural techniques, particularly cryo-electron microscopy (cryoEM) and ...
Morganne Wilbourne, Peijun Zhang
doaj +1 more source
Nuclear restriction of HIV-1 infection by SUN1
Scientific Reports, 2021 Overexpression of the human Sad-1-Unc-84 homology protein 2 (SUN2) blocks HIV-1 infection in a capsid-dependent manner. In agreement, we showed that overexpression of SUN1 (Sad1 and UNC-84a) also blocks HIV-1 infection in a capsid-dependent manner.
Mirjana Persaud +6 more
doaj +1 more source
Feline Calicivirus Capsid Protein Expression and Capsid Assembly in Cultured Feline Cells [PDF]
Journal of Virology, 1999 ABSTRACT The capsid protein of feline calicivirus (FCV) was expressed by using plasmids containing cytomegalovirus, simian virus 40, or T7 promoters. The strongest expression was achieved with the T7 promoter and coinfection with vaccinia virus expressing the T7 RNA polymerase (MVA/T7pol). The FCV precursor capsid protein was processed to the
K, Geissler +5 more
openaire +2 more sources