Results 41 to 50 of about 5,586,089 (360)
Scientific Reports, 2022 Marseilleviridae is a family of giant viruses, showing a characteristic internal membrane with extrusions underneath the icosahedral vertices. However, such large objects, with a maximum diameter of 250 nm are technically difficult to examine at sub ...
Akane Chihara +6 more
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Journal of General Virology, 2005 The rotavirus capsid is made up of three concentric protein layers. The outer layer, consisting of VP7 and VP4, is lost during virus entry into the host cell. Rotavirus field isolates can be adapted to high-titre growth in tissue culture by treatment with trypsin and by supplementing the culture medium with trypsin, which cleaves VP4 into two fragments,
Benureau, Yann +4 more
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Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly
Communications Biology, 2022 A 2.9 Å resolution structure of the L-BC virus provides insight into the contacts between capsid proteins and the mechanism of capsid assembly.
Danyil Grybchuk +6 more
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Virology, 1998 The genome of Helminthosporium victoriae 190S totivirus (Hv190SV) consists of two large overlapping open reading frames (ORFs), encoding a capsid protein (CP) and an RNA-dependent RNA polymerase. The capsid of Hv190SV, even though encoded by a single gene, contains three closely related capsid polypeptides: p88, p83, and p78.
Ana I. Soldevila +2 more
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Diagnostic Potential of Parechovirus Capsid Proteins [PDF]
Journal of Clinical Microbiology, 2003 ABSTRACT To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S -transferase (GST)-tagged recombinant proteins. The fusion proteins were used to raise antisera in rabbits.
Timo Hyypiä +4 more
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The dynamics of viruslike capsid assembly and disassembly [PDF]
Journal of the American Chemical Society 2022 144 (28),
12608-12612, 2022 Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A major challenge lies in distinguishing between the roles of the interaction between coat proteins and that between the coat proteins and the viral RNA in assembly and disassembly processes.
arxiv +1 more source
The papillomavirus major capsid protein L1
Virology, 2013 The elegant icosahedral surface of the papillomavirus virion is formed by a single protein called L1. Recombinant L1 proteins can spontaneously self-assemble into a highly immunogenic structure that closely mimics the natural surface of native papillomavirus virions. This has served as the basis for two highly successful vaccines against cancer-causing
Patricia M. Day +2 more
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Structure of the herpesvirus major capsid protein [PDF]
The EMBO Journal, 2003 Herpes simplex virus-1 (HSV-1) virions are large, complex enveloped particles containing a proteinaceous tegument layer connected to an icosahedral capsid. The major capsid protein, VP5 (149 kDa), makes up both types of capsomere, pentons and hexons. Limited trypsin digestion of VP5 identified a single stable 65 kDa fragment which represents a proposed
Matthew L. Baker +4 more
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Adeno-associated virus capsid assembly is divergent and stochastic
Nature Communications, 2020 Adeno-associated viruses (AAVs) are increasingly used as gene therapy vectors. AAVs package their genome in a non-enveloped T = 1 icosahedral capsid of ~3.8 megaDalton, consisting of 60 subunits of 3 distinct viral proteins (VPs), which vary only in ...
Tobias P. Wörner +7 more
semanticscholar +1 more source
Production of FMDV virus-like particles by a SUMO fusion protein approach in
Journal of Biomedical Science, 2009 Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid proteins from many viruses. Some VLPs have been proven successful as vaccines, and others have recently found applications as carriers for foreign antigens or as ...
Liang Shu-Mei +3 more
doaj +1 more source