Results 31 to 40 of about 133,853 (200)
Metagenomics analysis reveals features unique to Indian distal gut microbiota.
PLoS ONE, 2020 Various factors including diet, age, geography, culture and socio-economic status have a role in determining the composition of the human gut microbiota. The human gut microbial composition is known to be altered in disease conditions.
Kamaldeep Kaur +4 more
doaj +1 more source
The Indian Journal of Agricultural Sciences, 2019 Karnal bunt of wheat is an internationally quarantined disease. One of the major constraints in exporting wheat is prevalence of Karnal bunt (KB). It is caused by Tilletia indica which is a heterothallic fungus and requires fusion of different mating ...
JAGMOHAN SINGH +4 more
doaj +1 more source
Homology to peptide pattern for annotation of carbohydrate-active enzymes and prediction of function
BMC Bioinformatics, 2017 Background Carbohydrate-active enzymes are found in all organisms and participate in key biological processes. These enzymes are classified in 274 families in the CAZy database but the sequence diversity within each family makes it a major task to ...
P. K. Busk +4 more
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Carbohydrate‐active enzymes exemplify entropic principles in metabolism
Molecular Systems Biology, 2011 Glycans comprise ubiquitous and essential biopolymers, which usually occur as highly diverse mixtures. The myriad different structures are generated by a limited number of carbohydrate‐active enzymes (CAZymes), which are unusual in that they catalyze ...
Önder Kartal +3 more
doaj +1 more source
Scientific Reports, 2021 Bacteroidetes are efficient degraders of complex carbohydrates, much thanks to their use of polysaccharide utilization loci (PULs). An integral part of PULs are highly specialized carbohydrate-active enzymes, sometimes composed of multiple linked domains
Cathleen Kmezik +3 more
doaj +1 more source
Frontiers in Microbiology, 2022 Enteric methane (CH4) emission from cattle is strongly linked to the feeding regime and the rumen microbial community structure. Here, we report that feed-induced CH4-reducing effects correlate with specific alterations in the profile of the microbiome ...
Kristian Barrett +5 more
doaj +1 more source
The Impact of DNA Methylation in Trichoderma reesei on Cellulase Production and Strain Degeneration
MicroorganismsThe spontaneous loss of cellulase productivity of industrial T. reesei strains during production results in significant economic losses. This phenomenon was suggested to be epigenetically regulated, but the previous findings did not explain which ...
Caroline Danner +3 more
doaj +1 more source
Exploration of Trichoderma reesei as an alternative host for erythritol production
Biotechnology for Biofuels and BioproductsBackground Erythritol, a natural polyol, is a low-calorie sweetener synthesized by a number of microorganisms, such as Moniliella pollinis. Yet, a widespread use of erythritol is limited by high production costs due to the need for cultivation on glucose-
Audrey Masi +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source