Carboxymethyllysine and carboxyethyllysine in multiple sclerosis patients
Archives of Medical Science, 2020 Introduction Advanced glycation end-products (AGE) are involved in the pathogenesis of many diseases, including neurodegenerative diseases such as multiple sclerosis (MS).
Aleksandra Damasiewicz-Bodzek +3 more
doaj +2 more sources
Effect of Nɛ-carboxymethyllysine on oxidative stress and the glutathione system in beta cells
Toxicology Reports, 2014 One of the pathways involved in the pathogenesis of diabetic complications is the formation of excessive levels of advanced glycation end (AGE) products. Nɛ-carboxymethyllysine (CML) is one of the best-characterized AGEs.
Daniëlle M.P.H.J. Boesten +4 more
doaj +2 more sources
Molecules, 2019 The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the Nε-carboxymethyllysine (CML) formation from dairy food were investigated.
Yuzhen Wang +6 more
doaj +2 more sources
CIGB-258, a Potential Novel Approach to Treat Sepsis-like Hyperinflammation, Reduces Gastrointestinal Hemorrhage in Zebrafish Exposed to Carboxymethyllysine and Ethanol [PDF]
PharmaceuticalsObjective: CIGB-258 is a 3 KDa altered peptide ligand recognized for its anti-inflammatory activity. Herein, the effect of CIGB-258 was assessed against carboxymethyllysine (CML) and ethanol (Et-OH)-induced sepsis-like events in zebrafish (Danio rerio ...
Kyung-Hyun Cho +5 more
doaj +2 more sources
Biomedicines, 2021 Objective: Elevated levels of serum Nε-carboxymethyllysine (CML), a well-known advanced glycation end-product (AGE), were observed in patients with inflammation or osteoporosis.
A. N. M. Mamun-Or-Rashid +3 more
doaj +2 more sources
Phosphorylated Alpha-Synuclein and Carboxymethyllysine in the Epidermis of Type 2 Diabetes Patients: Preliminary Observations [PDF]
BiomedicinesBackground/objectives: Alpha-synuclein (aSyn) is best known for its role in Parkinson’s disease. Increasing evidence suggests a bidirectional relationship between diabetes mellitus and synuclein pathology. Carboxymethyllysine (CML), an advanced glycation
Bernard Kordas +3 more
doaj +2 more sources
Assessment of the correlations among 1,2-dicarbonyl compounds, advanced glycation end products, and raw material chemical components of fried shiitake mushroom (Lentinula edodes) crisps [PDF]
Food Chemistry: XThis study investigated the formation of harmful Maillard reaction products (MRPs), particularly advanced glycation end products (AGEs) and 1,2-dicarbonyl compounds, in fried shiitake mushroom crisps prepared from ten types of Lentinula edodes, in ...
Yong Li +6 more
doaj +2 more sources
Antioxidants, 2023 Ozonated sunflower oil (OSO) is an established therapeutic agent and nutraceutical harboring various therapeutic values, including antiallergic, derma-protective, and broad-spectrum antimicrobial activity.
Kyung-Hyun Cho +3 more
doaj +2 more sources
Stigmasterol-Based EGCG Liposomes Reduce Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL) in a Model System and Cookies [PDF]
Foods(–)-Epigallocatechin gallate (EGCG) is a promising inhibitor for the formation of advanced glycation end products. However, its instability limits its application in complex food systems. In this study, EGCG was encapsulated into liposomes prepared using
Xinyu Liu +4 more
doaj +2 more sources
Antioxidants, 2023 Ozonated sunflower oil (OSO) is a well-known functional oil with antioxidant, antimicrobial, anti-allergic, and skin-moisturizing properties. However, studies on the effects of OSO on high-cholesterol diet (HCD)-induced metabolic disorders have been ...
Kyung-Hyun Cho +3 more
doaj +2 more sources