Results 31 to 40 of about 1,364 (167)

Heat-induced formation of advanced glycation end-products in ground pork as affected by the addition of acetic acid or citric acid and the storage duration prior to the heat treatments

Food Chemistry: X, 2022
The heat-induced (121 °C, 10 or 30 min) formation of two potentially hazardous advanced glycation end-products (AGEs), protein-bound Nɛ-carboxymethyllysine (CML) and Nɛ-carboxyethyllysine (CEL), in pork as affected by citric or acetic acid (0.5, 1 g/100 ...
Hui Lin, Keqiang Lai, Juanjuan Zhang, Faxiang Wang, Yongle Liu, Barbara A Rasco, Yiqun Huang   +6 more
doaj   +1 more source

Dataset for Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N(6)-Carboxymethyllysine

, 2022
Microglial function declines during aging. The interaction of microglia with the gut microbiota has been well characterized during development and adulthood, but not in aging.
Omar Mossad (11990199), Bahtiyar Yilmaz (5872634), Thomas Blank (11990196)   +2 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +27 more
wiley   +1 more source

The Effect of Free and Protein‐Bound Maillard Reaction Products N‐ε‐Carboxymethyllysine, N‐ε‐Fructosyllysine, and Pyrraline on Nrf2 and NFκB in HCT 116 Cells

Molecular Nutrition &Food Research, Volume 67, Issue 18, September 2023., 2023
Protein‐bound Maillard reaction products are assumed to interact with the receptor for advanced glycation endproducts (RAGE) and initiate inflammation. The structural basis for this interaction is scarcely studied. Lysine residues in casein were selectively modified to carboxymethyl lysine, fructosyllysine, and pyrraline.
Jana Raupbach, Stephan K. Müller, Vanessa Schnell, Suse Friedrich, Anne Hellwig, Tilman Grune, Thomas Henle   +6 more
wiley   +1 more source

Alterations in pro- and anti-inflammatory mediators are involved in microvascular dysfunction in postmenopausal women with type 2 diabetes mellitus [PDF]

Brazilian Journal of Medical and Biological Research, 2022
Evidence has shown that women with type 2 diabetes mellitus (T2DM) have a greater risk of cardiovascular complications compared with men, but this sex difference is not clearly understood.
A.P. Jarrete, L.T. Giollo-Junior, J.F. Vilela-Martin, I.P. Novais, M.A. Delbin, A. Zanesco   +5 more
doaj   +1 more source

Carboxymethyl Lysine Content in Plant-Based Meat Products and Its Developmental Toxicity in Zebrafish [PDF]

Shipin Kexue
To investigate the distribution of carboxymethyllysine (CML) in plant-based meat products and its toxic effects on zebrafish larvae, five representative commercially available plant-based meat products were selected.
LI Su, ZHAO Yan, PAN Xiaoqian, FU Xiaohang, LIANG Erhong, ZHAO Bing, ZHANG Shunliang
doaj   +1 more source

Investigation of Advanced Glycation End-Products, α-Dicarbonyl Compounds, and Their Correlations with Chemical Composition and Salt Levels in Commercial Fish Products

Foods, 2023
The contents of free and protein-bound advanced glycation end-products (AGEs) including Nε-carboxymethyllysine (CML) and Nε-carboxyethyllysine (CEL), along with glyoxal (GO), methylglyoxal (MGO), chemical components, and salt in commercially prepared and
Lihong Niu, Shanshan Kong, Fuyu Chu, Yiqun Huang, Keqiang Lai   +4 more
doaj   +1 more source

Expedient synthesis of peptides containing Nε- carboxymethyllysine [PDF]

, 2014
Accumulation of advanced glycation endproducts (AGEs) is responsible for the development and progress of diabetes- and age-related complications. Synthesis of specific chemical probes is key for the detailed understanding of biochemical properties of ...
Brimble, Margaret A., Harris, Paul W R, Yang, Sunghyun, Kamalov, Meder, Cooper, Garth   +4 more
core   +1 more source

High serum levels of N-epsilon-carboxymethyllysine are associated with poor coronary collateralization in type 2 diabetic patients with chronic total occlusion of coronary artery

BMC Cardiovascular Disorders, 2022
Background The formation of advanced glycation end-products (AGEs) is a crucial risk factor for the pathogenesis of cardiovascular diseases in diabetes.
Le-Ying Li, Shuai Chen, Fei-Fei Li, Zhi-Ming Wu, Ying Shen, Feng-Hua Ding, Xiao-Qun Wang, Wei-Feng Shen, Qiu-Jing Chen, Yang Dai, Lin Lu   +10 more
doaj   +1 more source

Effects of Formulation and Baking Conditions on Neo-formed Contaminants in Model Cookies

Czech Journal of Food Sciences, 2009
This work aimed at studying the influence of baking temperature and formulation on the formation of undesirable Maillard compounds called neoformed contaminants (NFC) in a model cookie system.
M. Courel, L. Ait-Ameur, E. Capuano, V. Fogliano, F. J. Morales, F. Courtois, I. Birlouez-Aragon   +6 more
doaj   +1 more source