Results 41 to 50 of about 1,364 (167)

Anaerobic Degradation of N-ϵ-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria

open access: yes, 2019
Modifications of lysine contribute to the amount of dietary advanced glycation end-products reaching the colon. However, little is known about the ability of intestinal bacteria to metabolize dietary N-ϵ-carboxymethyllysine (CML). Successive transfers of
Fogliano, Vincenzo   +3 more
core   +2 more sources

Aerobic Exercise Training Reduces Atherogenesis Induced by Low-Sodium Diet in LDL Receptor Knockout Mice

open access: yesAntioxidants, 2022
This study investigated the efficacy of aerobic exercise training (AET) in the prevention of dyslipidemia, insulin resistance (IR), and atherogenesis induced by severe low-sodium (LS) diet. LDL receptor knockout (LDLR KO) mice were fed a low-sodium (LS) (
Ana Paula Garcia Bochi   +14 more
doaj   +1 more source

Controlled Formation of Carboxymethyllysine in Bone Matrix through Designed Glycation Reaction

open access: yesJBMR Plus, 2021
It has been a challenge to establish a link between specific advanced glycation end products (AGEs) as causal agents of different pathologies and age‐related diseases, primarily because of the lack of suitable in vitro experimental strategies ...
Grażyna E. Sroga, Deepak Vashishth
doaj   +1 more source

Correlation of nitric oxide (NO) with pentosidine and carboxymethyllysine (CML).

open access: yes, 2019
Correlation of nitric oxide (NO) with pentosidine and carboxymethyllysine (CML).
Sorayya Kheirouri (6444476)   +3 more
core   +1 more source

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

open access: yes, 2022
Microglial function declines during aging. The interaction of microglia with the gut microbiota has been well characterized during development and adulthood but not in aging.
Maron, F.   +45 more
core   +1 more source

Advanced Glycation End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE)

open access: yesCells, 2021
Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak   +5 more
doaj   +1 more source

Nε-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction

open access: yes, 2015
N(ε)-carboxymethyllysine (CML) is an important driver of diabetic vascular complications and endothelial cell dysfunction. However, how CML dictates specific cellular responses and the roles of protein tyrosine phosphatases and ERK phosphorylation remain
Sheu, Meei-Ling   +14 more
core   +2 more sources

The AGE-RAGE Axis and Its Relationship to Markers of Cardiovascular Disease in Newly Diagnosed Diabetic Patients. [PDF]

open access: yesPLoS ONE, 2016
The purpose of the study was the simultaneous measurement of all the different components of the AGE-RAGE axis as well as several non-invasive markers of cardiovascular disease (CVD) in a cohort of newly diagnosed diabetic patients.In 80 newly diagnosed ...
Ma Etzabel Villegas-Rodríguez   +8 more
doaj   +1 more source

Air frying combined with grape seed extract inhibits Nε-carboxymethyllysine and Nε-carboxyethyllysine by controlling oxidation and glycosylation

open access: yesPoultry Science, 2021
Advanced glycation end products (AGE), compounds formed in meat at the advanced stage of Maillard reaction, are easily exposed to thermal processing. Improving cooking condition and adding antioxidants are 2 common ways for AGE reduction.
Zongshuai Zhu   +5 more
doaj   +1 more source

Renal N(epsilon)-carboxymethyllysine deposition after kidney transplantation.

open access: yes, 2008
BACKGROUND: Accumulation of advanced glycation end products, that is, N(epsilon)-carboxymethyllysine (CML), induces oxidative stress and inflammation, and is present in chronic renal failure.
Baumann, M;Caron, M;Schmaderer, C;Schulte, C;Viklický, O;von Weyhern, CW;Lutz, J;Heemann, U
core   +1 more source

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