Results 61 to 70 of about 1,364 (167)

N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response

, 2008
Advanced glycation endproducts (AGEs) containing carboxymethyllysine (CML) modifications are generally thought to be ligands of the receptor for AGEs, RAGEs. It has been argued that this results in the activation of pro-inflammatory pathways and diseases.
Newell, J, Junod, S, Leclerc, E, Maurer, S, Adolfsson, O, Buetler, T M, Baumeyer, A, Piguet, D, Richoz, J, Heizmann, C W, Foata, F, Latado, H, Delatour, T, Parisod, V   +13 more
core   +1 more source

Association Between Serum Advanced Glycation End Products and Cardiovascular‐Kidney‐Metabolic (CKM) Syndrome: A 3‐Year Longitudinal Cohort Study (2019–2022)

Journal of Diabetes, Volume 17, Issue 8, August 2025.
Our study reveals that elevated serum Advanced glycation end products (AGEs) are significantly associated with both the severity and progression of cardiovascular‐kidney‐metabolic (CKM) syndrome. The findings demonstrate dose‐dependent severity associations (adjusted OR = 1.92, Q4 vs. Q1) and predict 3‐year disease worsening (high‐risk vs. low‐risk: OR 
Hui Zhao, Ze‐wen Zhang, Tao Luo, Dilihumaer Aili, Wen‐huan Ding, Yuan‐yuan Li, Yuan‐sheng Gu, Shulipan Aslibek, Jing‐jing He, Wen‐hui Yu, Run‐ze Ma, Anaer Gaoshao, Ting‐ting Qiao, Guo‐zhen Zhang, Henry S. Lynn, Mu‐long Du, Jiang‐hong Dai   +16 more
wiley   +1 more source

Anaerobic Degradation of N‑ε-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria

, 2019
Modifications of lysine contribute to the amount of dietary advanced glycation end-products reaching the colon. However, little is known about the ability of intestinal bacteria to metabolize dietary N-ε-carboxymethyllysine (CML). Successive transfers of
Vincenzo Fogliano (290943), Vincenzo Fogliano, Willem M. de Vos, Thi Phuong Nam Bui (6744176), Willem M. de Vos (183481), Thi Phuong Nam Bui, Antonio Dario Troise, Antonio Dario Troise (6744179)   +7 more
core   +1 more source

Maillard reaction products in plant-based dairy alternatives and their release during simulated gastrointestinal digestion

Current Research in Food Science
Plant-based food products are becoming increasingly popular among consumers. The chemical composition and the processing of plant-based products presumably fuel the Maillard reaction, but the abundance of Maillard reaction products in plant-based food ...
Kira Bieck, Franziska Ebert, Tilman Grune, Jana Raupbach   +3 more
doaj   +1 more source

Exploring the Effects of Plant‐Based Ingredients and Phytochemicals on the Formation of Advanced Glycation End Products in Bakery Products: A Systematic Review

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
This systematic review highlights the potential activity of plant‐based ingredients and phytochemicals to reduce the formation of AGEs and α‐dicarbonyl compounds in bakery products. The examined studies demonstrated that various phytochemicals, including flavonoids, phenolic acids, stilbenes, and other polyphenols, as well as various plant extracts and
Busra Turan‐Demirci, Buket Gonen‐Colak, Zehra Buyuktuncer   +2 more
wiley   +1 more source

Exploring the role of body mass index in relationship of serum nitric oxide and advanced glycation end products in apparently healthy subjects.

PLoS ONE, 2019
This study aimed to identify any association of serum nitric oxide (NO) and advanced glycation end products (AGEs) with body mass index (BMI) in apparently healthy subjects. In this cross-sectional study, participants were 90 apparently healthy subjects,
Elaheh Foroumandi, Mohammad Alizadeh, Sorayya Kheirouri, Mohammad Asghari Jafarabadi   +3 more
doaj   +1 more source

Effect of Freeze-Thaw Cycles on the Oxidation of Protein and Fat and Its Relationship with the Formation of Heterocyclic Aromatic Amines and Advanced Glycation End Products in Raw Meat

Molecules, 2021
The aim of this research was to investigate the effect of the number of freeze–thaw cycles (0, 1, 3, 5, and 7) on porcine longissimus protein and lipid oxidation, as well as changes in heterocyclic aromatic amines (HAAs) and advanced glycation end ...
Xingge Wu, Zhigang Zhang, Zhiyong He, Zhaojun Wang, Fang Qin, Maomao Zeng, Jie Chen   +6 more
doaj   +1 more source

Nutritional safety and suitability of a specific protein hydrolysate derived from sources of skimmed cow's milk and whey protein concentrates and used in infant and follow‐on formula manufactured from hydrolysed protein by Healthcare Reckitt B.V.

EFSA Journal, Volume 23, Issue 3, March 2025.
Abstract The European Commission (EC) requested the European Food Safety Authority to evaluate the nutritional safety and suitability of a specific protein hydrolysate derived from sources of skimmed cow's milk (including non‐fat) and whey protein concentrates for use in infant and follow‐on formula manufactured by Healthcare Reckitt B.V.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Angeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Laurence Castle, Mary Fewtrell, Hildegard Przyrembel, Ariane Titz, Dominique Turck   +19 more
wiley   +1 more source

Nutritional safety and suitability of a specific protein hydrolysate manufactured by Fonterra Co‐operative Group Ltd derived from a whey protein concentrate and used in infant formula and follow‐on formula

EFSA Journal, Volume 23, Issue 1, January 2025.
Abstract The European Commission asked EFSA to deliver an opinion on the nutritional safety and suitability for use in infant and follow‐on formula of a specific protein hydrolysate from whey protein concentrate manufactured by Fonterra Co‐operative Group Ltd. Fonterra Co‐operative Group Ltd. submitted a dossier to the European Commission to request an
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Angeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Laurence Castle, Mary Fewtrell, Hildegard Przyrembel, Ariane Titz, Dominique Turck   +19 more
wiley   +1 more source

Exposure of Caenorhabditis elegans to Dietary Nε-Carboxymethyllysine Emphasizes Endocytosis as a New Route for Intestinal Absorption of Advanced Glycation End Products

, 2021
International audienceThe impact of dietary advanced glycation end products (dAGEs) on human health has been discussed in many studies but, to date, no consensual pathophysiological process has been demonstrated.
Taront, Solenne, Frédéric J. Tessier, Litke, Rachel, Paul-Constant, Charles, Stéphane Rianha, Tessier, Frédéric, Fradin, Chantal, Jean-Marc Lo Guidice, Dubois, Constance, Lo Guidice, Jean-Marc, Charles Paul-Constant, Eric Boulanger, Rachel Litke, Boulanger, Eric, Chantal Fradin, Solenne Taront, Constance Dubois, Rianha, Stéphane   +17 more
core   +1 more source