Results 1 to 10 of about 9,304 (191)
Proteolytic Processing and Activation of
mBio, 2014 Epsilon toxin (ETX), a pore-forming toxin produced by type B and D strains of Clostridium perfringens, mediates severe enterotoxemia in livestock and possibly plays a role in human disease.
John C. Freedman +3 more
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Genetic interaction mapping reveals functional relationships between peptidoglycan endopeptidases and carboxypeptidases. [PDF]
PLoS GeneticsPeptidoglycan (PG) is the main component of the bacterial cell wall; it maintains cell shape while protecting the cell from internal osmotic pressure and external environmental challenges.
Manuela Alvarado Obando +3 more
doaj +2 more sources
Pharmaceutics, 2022 The yields of soluble ECM proteins recombinantly produced with mammalian cells can be significantly enhanced by exploiting the stabilizing properties of heparin.
Javier Garcia-Pardo +4 more
doaj +1 more source
Microbiology Spectrum, 2023 Peptidoglycan (PG) is an essential bacterial architecture pivotal for shape maintenance and adaptation to osmotic stress. Although PG synthesis and modification are tightly regulated under harsh environmental stresses, few related mechanisms have been ...
Umji Choi +4 more
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Comparative Modeling and Analysis of Extremophilic D-Ala-D-Ala Carboxypeptidases
Biomolecules, 2023 Understanding the molecular adaptations of organisms to extreme environments requires a comparative analysis of protein structure, function, and dynamics across species found in different environmental conditions.
Elizabeth M. Diessner +3 more
doaj +1 more source
Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings. [PDF]
PLoS ONE, 2017 Vasoactive and mitogenic peptide, endothelin-1 (ET-1) plays an important role in physiology of the ocular tissues by regulating the growth of corneal epithelial cells and maintaining the hemodynamics of intraocular fluids.
Xuefang Pan +4 more
doaj +1 more source
Microbiology Spectrum, 2022 Vancomycin and β-lactams are clinically important antibiotics that inhibit the formation of peptidoglycan cross-links, but their binding targets are different.
Si Hyoung Park +5 more
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Molecules, 2020 Proteomic technologies have identified 234 peptidases in plasma but little quantitative information about the proteolytic activity has been uncovered.
Elisa Maffioli +12 more
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The new effector AbSCP1 of foliar nematode (Aphelenchoides besseyi) is required for parasitism rice
Journal of Integrative Agriculture, 2022 Plant parasitic nematodes secrete effector proteins to parasitize hosts successfully. Of these proteins, serine carboxypeptidases have critical roles in pathogenicity.
Xin HUANG +5 more
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The effects of daptomycin on cell wall biosynthesis in Enterococcal faecalis
Scientific Reports, 2023 Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious infections by multidrug-resistant Gram-positive pathogens. Its mode of action is considered to be multifaceted, encompassing the targeting and depolarization of ...
Binayak Rimal +5 more
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