Results 61 to 70 of about 23,292 (261)

Iron-binding fragments from the N-Terminal and C-Terminal regions of human lactoferrin [PDF]

, 1978
Digestion of lactoferrin with pepsin at pH 3.0 gave an iron-binding half-molecule that represents the C-terminal part of the native protein. Tryptic or chymotryptic digestion of 30%/-iron-saturated lactoferrin yielded the N- and C-terminal half ...
Bluard-Deconinck, JM, Evans, RW, Massont, PL, Osinski, PA, Snick, JV, Williams, J   +5 more
core   +1 more source

Purification to homogeneity and properties of two D-alanine carboxypeptidases I From Escherichia coli.

Journal of Biological Chemistry, 1976
Three homogeneous preparations of D-alanine carboxypeptidases I have been obtained from Escherichia coli strain H2143, termed enzymes IA, IB, and IC.
Toshihide, Tamura, Jack, L. Strominger
semanticscholar   +1 more source

C‐Terminal Tail Elongation Adds a New Dimension to the Tubulin Code

Cytoskeleton, EarlyView.
ABSTRACT Tubulin C‐terminal tails undergo diverse post‐translational modifications that regulate microtubule interactions with motors and severing enzymes. TTLL11, a member of the tubulin tyrosine ligase‐like (TTLL) family, uniquely catalyzes glutamate addition to the terminal α‐carboxyl group of both α‐ and β‐primary tubulin tails.
Jana Campbell, Cyril Barinka
wiley   +1 more source

Monitoring of Carboxypeptidase Digestion by Matrix-Assisted Laser Desorption and Ionization Mass Spectrometry

CHIMIA, 1991
The potential of matrix-assisted laser desorption and ionization mass spectrometry (LDI-MS) is demonstrated by monitoring and analyzing the digestion of (human) pTH (1–34), a synthetic peptide with carboxypeptidases Y and B.
Martin Schär, K. Olaf Börnsen, Ernst Gassmann, H. Michael Widmer   +3 more
doaj   +2 more sources

Current Advances in Ochratoxin A-Degrading Enzymes [PDF]

Shipin Kexue
Ochratoxin A (OTA) poses a serious threat to human and animal health as well as the ecological environment due to its high toxicity, stable physicochemical properties, and widespread occurrence in food and feed.
NIU Zehui, LIANG Zhihong
doaj   +1 more source

From Data Mining of Chitinophaga sp. Genome to Enzyme Discovery of a Hyperthermophilic Metallocarboxypeptidase

Microorganisms, 2021
For several centuries, microorganisms and enzymes have been used for many different applications. Although many enzymes with industrial applications have already been reported, different screening technologies, methods and approaches are constantly being
Gabriela Cabral Fernandes, Elwi Guillermo Machado Sierra, Paul Brear, Mariana Rangel Pereira, Eliana G. M. Lemos   +4 more
doaj   +1 more source

Kinin-generating cellular model obtained from human glioblastoma cell line U-373 [PDF]

, 2013
Kinins, a group of important pro-inflammatory peptides, are abundantly found in tissues and biological fluids of cancer patients. Bradykinin, the major representative of kinins, induces vascular permeability and, in consequence, promotes tumor expansion.
Błońska, Beata, Faussner, Alexander, Guevara Lora, Ibeth, Kozik, Andrzej   +3 more
core   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.

PLoS Pathogens, 2020
Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics.
Federica Giordani, Daniel Paape, Isabel M Vincent, Andrew W Pountain, Fernando Fernández-Cortés, Eva Rico, Ning Zhang, Liam J Morrison, Yvonne Freund, Michael J Witty, Rosemary Peter, Darren Y Edwards, Jonathan M Wilkes, Justin J J van der Hooft, Clément Regnault, Kevin D Read, David Horn, Mark C Field, Michael P Barrett   +18 more
doaj   +1 more source

Peptides naturally generated from ubiquitin-60S ribosomal protein as potential biomarkers of dry-cured ham processing time [PDF]

, 2015
Proteolysis is a complex and dynamic process which takes place throughout the whole dry-cured processing due to the action of endogenous muscle peptidases, and results in the generation of a high number of small peptides and free amino acids responsible ...
Aristoy, María Concepción, Fraser, Paul D., Gallego, Marta, Mora, Leticia, Toldrá Vilardell, Fidel   +4 more
core   +2 more sources