Results 31 to 40 of about 862,015 (296)
Cardiac troponins in intensive care [PDF]
, 2005 The cardiac troponins are integral components of the myofibrillary apparatus and they regulate muscle contraction. The measurement of cardiac troponins has replaced other biomarkers for the specific detection of myocardial necrosis and for the diagnosis ...
Collinson, P.O. +3 more
core +1 more source
Defining the Cardiac Fibroblast
Circulation Journal, 2016 Cardiac fibrosis remains an important health concern, but the study of fibroblast biology has been hindered by a lack of effective means for identifying and tracking fibroblasts. Recent advances in fibroblast-specific lineage tags and reporters have permitted a better understanding of these cells.
Ivey, Malina J., Tallquist, Michelle D.
openaire +3 more sources
Redefining the identity of cardiac fibroblasts [PDF]
Nature Reviews Cardiology, 2017 Cardiac fibroblasts deposit and maintain extracellular matrix during organogenesis and under physiological conditions. In the adult heart, activated cardiac fibroblasts also participate in the healing response after acute myocardial infarction and during chronic disease states characterized by augmented interstitial fibrosis and ventricular remodelling.
Michelle D, Tallquist +1 more
openaire +2 more sources
Herzschrittmachertherapie + Elektrophysiologie, 2018 Fibrotic areas in cardiac muscle-be it in ventricular or atrial tissue-are considered as obstacles for conduction of the excitatory wave and can therefore facilitate re-entry, which may contribute to the sustenance of cardiac arrhythmias. Persistence of one of the most frequent arrhythmias, atrial fibrillation (AF), is accompanied by enhanced atrial ...
Klesen, Alexander +5 more
openaire +3 more sources
Exploring the cardiac ECM during fibrosis: A new era with next-gen proteomics
Frontiers in Molecular Biosciences, 2022 Extracellular matrix (ECM) plays a critical role in maintaining elasticity in cardiac tissues. Elasticity is required in the heart for properly pumping blood to the whole body. Dysregulated ECM remodeling causes fibrosis in the cardiac tissues.
Vivek Sarohi +5 more
doaj +1 more source
Analysis of Drosophila Fibroblast Growth Factor Functional Domains [PDF]
, 2011 The exciting Fibroblast Growth Factor (FGF) field lies at the crossroads of cell signaling, development, evolution, trafficking, physiology and human disease.
Tulin, Sarah Lynn
core +1 more source
Effect of β3-adrenoceptor on cardiac fibrosis in rat cardiac fibroblast cells and its potential mechanism [PDF]
, 2016 Purpose: To investigate the effect of β3-adrenoceptors (β3-AR) up-regulation on fibrosis in cardiac fibroblast cells in rats and its potential mechanism.Methods: Cardiac fibroblast cells (CFB) were isolated and identified from rats’ hearts.
Zhang, Hui +6 more
core +1 more source
Cells, 2022 Cardiac fibroblasts regulate the development of the adult cardiomyocyte phenotype and cardiac remodeling in disease. We investigate the role that cardiac fibroblasts-secreted extracellular vesicles (EVs) have in the modulation of cardiomyocyte Ca2 ...
Brian X. Wang +6 more
doaj +1 more source
Cardiac fibroblast in development and wound healing [PDF]
, 2014 Cardiac fibroblasts are the most abundant cell type in the mammalian heart and comprise approximately two-thirds of the total number of cardiac cell types. During development, epicardial cells undergo epithelial-mesenchymal-transition to generate cardiac
Ubil, Eric, Deb, Arjun
core +1 more source
Consequences of PDGFRα+ fibroblast reduction in adult murine hearts
eLife, 2022 Fibroblasts produce the majority of collagen in the heart and are thought to regulate extracellular matrix (ECM) turnover. Although fibrosis accompanies many cardiac pathologies and is generally deleterious, the role of fibroblasts in maintaining the ...
Jill T Kuwabara +14 more
doaj +1 more source