Results 11 to 20 of about 215,781 (262)
Cardiac Fibrosis and Fibroblasts [PDF]
Cells, 2021 Cardiac fibrosis is the excess deposition of extracellular matrix (ECM), such as collagen. Myofibroblasts are major players in the production of collagen, and are differentiated primarily from resident fibroblasts. Collagen can compensate for the dead cells produced by injury.
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Promising Therapeutic Treatments for Cardiac Fibrosis: Herbal Plants and Their Extracts
Cardiology and Therapy, 2023 Cardiac fibrosis is closely associated with multiple heart diseases, which are a prominent health issue in the global world. Neurohormones and cytokines play indispensable roles in cardiac fibrosis. Many signaling pathways participate in cardiac fibrosis
Xuejing Yu
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The pathogenesis of cardiac fibrosis [PDF]
Cellular and Molecular Life Sciences, 2013 Cardiac fibrosis is characterized by net accumulation of extracellular matrix proteins in the cardiac interstitium, and contributes to both systolic and diastolic dysfunction in many cardiac pathophysiologic conditions. This review discusses the cellular effectors and molecular pathways implicated in the pathogenesis of cardiac fibrosis.
Ping, Kong +2 more
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Zanubrutinib Ameliorates Cardiac Fibrosis and Inflammation Induced by Chronic Sympathetic Activation
Molecules, 2023 (1) Background: Heart failure (HF) is the final stage of multiple cardiac diseases, which have now become a severe public health problem worldwide.
Wenqi Li +14 more
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Chemokines and cardiac fibrosis [PDF]
Frontiers in Bioscience, 2009 Several members of the chemokine family play an important role in reparative fibrosis and are involved in the pathogenesis of remodeling following myocardial infarction. Chemokines may regulate the fibrotic process through recruitment and activation of mononuclear cell subsets and fibroblast progenitors (fibrocytes), by exerting direct effects on ...
Marcin, Dobaczewski +1 more
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Molecules, 2022 Cardiac fibrosis is a common pathophysiologic process in nearly all forms of heart disease which refers to excessive deposition of extracellular matrix proteins by cardiac fibroblasts.
Ruiqiang Qi +4 more
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Endothelins and Cardiac Fibrosis [PDF]
Hypertension, 1999 To the Editor: In the March issue of Hypertension , Dr Hocher and colleagues reported on the role of the endothelin (ET) system in the cardiac remodeling of renovascular hypertension.1 According to their findings, both fibrosis of the left ventricle (LV) and hypertrophy of intracardiac arteries were markedly prevented in the 2-kidney, 1-clip (2K1C ...
G P, Rossi, M, Cesari, A C, Pessina
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Biology Direct, 2022 Background Cardiac fibrosis is a leading cause of cardiac dysfunction in patients with diabetes. However, the underlying mechanisms of cardiac fibrosis remain unclear.
Tingwei Peng +12 more
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Different Roles of Resident and Non-resident Macrophages in Cardiac Fibrosis
Frontiers in Cardiovascular Medicine, 2022 Cardiac fibrosis is a key pathological link of various cardiovascular diseases to heart failure. It is of great significance to deeply understand the development process of cardiac fibrosis and the cellular and molecular mechanisms involved.
Siyuan Hu +14 more
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ADAMTS8 Promotes Cardiac Fibrosis Partly Through Activating EGFR Dependent Pathway
Frontiers in Cardiovascular Medicine, 2022 Myocardial infarction or pressure overload leads to cardiac fibrosis, the leading cause of heart failure. ADAMTS8 (A disintegrin and metalloproteinase with thrombospondin motifs 8) has been reported to be involved in many fibrosis-related diseases ...
Yafang Zha +6 more
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