Results 81 to 90 of about 126,969 (147)

Simultaneous determination of natural and synthetic steroid estrogens and their conjugates in aqueous matrices by liquid chromatography / mass spectrometry [PDF]

, 2005
An analytical method for the simultaneous determination of nine free and conjugated steroid estrogens was developed with application to environmental aqueous matrices.
Scrimshaw, MD, Lester, JN, Gomes, RL, Birkett, JW, Scrimshaw, Mark D., Gomes, Rachel L., Birkett, Jason W., Lester, John N.   +7 more
core   +1 more source

Bufalin Suppresses Colorectal Cancer Liver Metastasis by Inhibiting De Novo Fatty Acid Synthesis via the PI3K/AKT-Mediated SREBP1/FASN Pathway

Molecules
Background: Colorectal cancer (CRC) is the third most common cancer worldwide, with liver metastasis being the leading cause of mortality. De novo fatty acid synthesis plays a critical role in CRC progression and metastasis.
Wenwen Pang, Xiang Li, Suying Yan, Junshi Zhang, Ping Wu, Haiyang Yu, Bowei Zhang, Chunze Zhang   +7 more
doaj   +1 more source

REGULATION OF HEPATIC STEROID METABOLISM BY THE HYPOTHALAMO-PITUITARY-LIVER AXIS

, 1981
This chapter discusses the regulation of hepatic steroid metabolism by the hypothalamo-pituitary-liver axis. The pituitary gland is essential for the maintenance of the female type of steroid metabolism in the adult animal.
HÖKFELT, T, P. ENEROTH, T. HÖKFELT, NORSTEDT, G, MODE, A, GUSTAFSSON, J-Å, G. NORSTEDT, ENEROTH, P, J.-Å. GUSTAFSSON, A. MODE   +9 more
core   +1 more source

The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells.

PLoS Pathogens, 2019
Human respiratory syncytial virus (RSV) is the leading viral cause of acute pediatric lower respiratory tract infections worldwide, with no available vaccine or effective antiviral drug. To gain insight into virus-host interactions, we performed a genome-
Matthias Lingemann, Thomas McCarty, Xueqiao Liu, Ursula J Buchholz, Sonja Surman, Scott E Martin, Peter L Collins, Shirin Munir   +7 more
doaj   +1 more source

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Morio Yamada, Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita   +3 more
core  

Cyclosporine A and steroid therapy in childhood steroid-resistant nephrotic syndrome

, 2010
Gargah Tahar, Lakhoua M RachidDepartment of Pediatric Nephrology, Charles Nicolle Hospital, Tunis, TunisiaBackground: In children, idiopathic nephrotic syndrome (INS) is primarily treated using corticosteroids.
Lakhoua M Rachid, Gargah Tahar
core   +1 more source

The steroid-binding properties of recombinant glucocorticoid receptor: a putative role for heat shock protein hsp90

, 1990
The steroid-binding domain of the human glucocorticoid receptor was expressed in Escherichia coli either as a fusion protein with protein A or under control of the T7 RNA polymerase promoter.
Ohara-Nemoto, Y, Carlstedt-Duke, J, Gustafsson, JA, Strömstedt, PE, Dahlman-Wright, K, Nemoto, T   +5 more
core   +1 more source

Cardiotonic Steroids Suppress Adenovirus Replication [PDF]

, 2018
Human adenoviruses are common pathogens that can cause life-threatening illness, yet no approved therapies are available for treatment. This work shows that two cardiotonic steroids, digoxin and digitoxin, inhibit adenovirus replication in A549 lung ...
Grosso, Filomena Sarina
core   +1 more source

Perioperative Marinobufagenin (MBG) Measurement May Improve Acute Kidney Injury Risk Assessment in Patients Undergoing Major Cardiac Surgery: A Proof-of-Concept Study

Medicina
Background and Objectives: Acute kidney injury (AKI) remains a significant complication following major cardiac surgery. Marinobufagenin (MBG), a cardiotonic steroid involved in sodium balance and blood pressure regulation, has been linked to organ ...
Davide Bolignano, Giuseppe Filiberto Serraino, Patrizia Pizzini, Federica Jiritano, Mariateresa Zicarelli, Belinda Spoto, Marco Mobrici, Michela Musolino, Désirée Napolitano, Alessandra Testa, Michele Andreucci, Pasquale Mastroroberto, Giuseppe Coppolino   +12 more
doaj   +1 more source

The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study. [PDF]

Nutrients, 2020
Strauss-Kruger M, Kruger R, Smith W, Gafane-Matemane LF, Mokwatsi G, Wei W, Fedorova OV, Schutte AE.   +7 more
europepmc   +1 more source