Results 71 to 80 of about 126,969 (147)
Toxins, 2020 The biological activity of Rhinella icterica parotoid secretion (RIPS) and some of its chromatographic fractions (RI18, RI19, RI23, and RI24) was evaluated in the current study. Mass spectrometry of these fractions indicated the presence of sarmentogenin,
Raquel Soares Oliveira +12 more
doaj +1 more source
The Scientific World Journal, Volume 2026, Issue 1, 2026.Nicotiana tabacum is a cash crop that originated in America and was introduced to the world by Christopher Colombus. It is now cultivated in many countries with major producers including China, the USA, India, and Brazil. The plant was widely used by the indigenous people of America for different reasons (spiritual, hallucination, and medical).
Abir Chami +4 more
wiley +1 more source
The Scientific World Journal, Volume 2026, Issue 1, 2026.Respiratory tract infections (RTIs) are the primary cause of morbidity and mortality in many low‐and middle‐income countries. In most of these countries, including Tanzania, medicinal plants (MPs) are primarily used to manage various ailments, though the majority are not yet documented.
Neema Gideon Mogha +4 more
wiley +1 more source
Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells
Cell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros +3 more
wiley +1 more source
Bibliographic Studies on the Bufonis Venenum
Journal of Pharmacopuncture, 2001 Objectives : Through the literatures on the effets of Bufonis Venenum, we are finding out the clinical possibility and revealing the more effective to intractable diseases. Methods : We investigated the literatures of Oriental Medicine and experimental
Kye-Sung Kang, Gi-Rok Kwon
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundExperimental uremic cardiomyopathy causes cardiac fibrosis and is causally related to the increased circulating levels of the cardiotonic steroid, marinobufagenin (MBG), which signals through Na/K‐ATPase. Rapamycin is an inhibitor of the serine/
Steven T. Haller +13 more
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Frontiers in PharmacologyDiffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL), with an increasing incidence in recent years. Ouabain, a cardiotonic steroid, has demonstrated anti-tumor effects in various cancers including DLBCL, but its ...
Yuan Wei +17 more
doaj +1 more source
Cancer Medicine, 2018 Malignant glioma is one of the most challenging central nervous system diseases to treat and has high rates of recurrence and mortality. Current therapies often fail to control tumor progression or improve patient survival.
Yu‐Long Lan +8 more
doaj +1 more source
Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats. [PDF]
Int J Mol Sci, 2022 Grigorova YN +13 more
europepmc +1 more source