Results 11 to 20 of about 78,724 (215)

Optimal DL-Methionyl-DL-Methionine Supplementation Improved Intestinal Physical Barrier Function by Changing Antioxidant Capacity, Apoptosis and Tight Junction Proteins in the Intestine of Juvenile Grass Carp (Ctenopharyngodon idella)

open access: yesAntioxidants, 2022
The present study was a part of a larger research project that aimed to investigate the effects of Met-Met supplementation on fish growth and intestinal health. This study mainly focused on the relationship between dietary Met-Met and intestinal physical
Pei Wu   +8 more
doaj   +1 more source

Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila

open access: yeseLife, 2017
Apoptosis and its molecular mediators, the caspases, have long been regarded as tumor suppressors and one hallmark of cancer is ‘Evading Apoptosis’.
Ernesto Pérez   +2 more
doaj   +1 more source

Expression of Apoptosis-Related Genes in Cat Testicular Tissue in Relation to Sperm Morphology and Seasonality—A Preliminary Study

open access: yesAnimals, 2021
Apoptosis is a crucial process in spermatogenesis, responsible for the elimination of abnormal sperm cells and testicular regression out of breeding season.
Sylwia Prochowska   +2 more
doaj   +1 more source

Combined RhoA morpholino and ChABC treatment protects identified lamprey neurons from retrograde apoptosis after spinal cord injury

open access: yesFrontiers in Cellular Neuroscience, 2023
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of chondroitin sulfate proteoglycans (CSPGs) at the site of injury with chondroitinase ABC (ChABC), each can reduce retrograde neuronal ...
Jianli Hu   +9 more
doaj   +1 more source

Effector Caspases and Leukemia

open access: yesInternational Journal of Cell Biology, 2011
Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes.
Ying Lu, Guo-Qiang Chen
doaj   +1 more source

Brainiac Caspases: Beyond the Wall of Apoptosis

open access: yesFrontiers in Cellular Neuroscience, 2019
For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions.
Ana María Espinosa-Oliva   +3 more
doaj   +1 more source

Apoptosis Regulators Bcl-2 and Caspase-3

open access: yesEncyclopedia, 2022
Apoptosis, programmed cell death, has a central role in developmental biology and in maintaining the equilibrium of renewing tissues. A founding member of the Bcl-2 family of regulatory proteins for apoptosis is Bcl-2, which is encoded by the BCL2 gene ...
Piret Hussar
doaj   +1 more source

Impact of Tau on Neurovascular Pathology in Alzheimer's Disease

open access: yesFrontiers in Neurology, 2021
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most prevalent cause of dementia. The main cerebral histological hallmarks are represented by parenchymal insoluble deposits of amyloid beta (Aβ plaques) and neurofibrillary tangles
Elisa Canepa, Silvia Fossati
doaj   +1 more source

E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1

open access: yesBiology, 2021
Apoptosis is a very important process of cell death controlled by multiple genes during which cells undergo certain events before dying. Apoptosis helps to clean the unnecessary cells and has critical physiological significance. Altered apoptosis results
Ge Yang   +7 more
doaj   +1 more source

Inhibitor of apoptosis proteins as E3 ligases for ubiquitin and NEDD8

open access: yesBiomolecular Concepts, 2013
The inhibitors of apoptosis proteins (IAPs) are endogenous inhibitors for apoptosis. Apoptosis is carried out by caspases, which are the family of cystein proteases. IAPs regulate caspases through two conserved regions, the baculovirus IAP repeats (BIRs)
Kamada Shinji
doaj   +1 more source

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