Results 11 to 20 of about 90,413 (210)
BMC Genomics, 2021 Background Apoptosis is an important process for an organism’s innate immune system to respond to pathogens, while also allowing for cell differentiation and other essential life functions.
Susanne Vogeler +3 more
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Identification and functional characterization of two executioner caspases in Crassostrea gigas. [PDF]
PLoS ONE, 2014 Caspase-3 and caspase-7 are two key effector caspases that play important roles in apoptotic pathways that maintain normal tissue and organ development and homeostasis.
Tao Qu +8 more
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Anti-Proliferative and Apoptotic Activities of Rumex crispus
Life, 2023 Colorectal cancer is the fourth leading cause of cancer death and the third most common cancer diagnosed in the United States. Several anticancer compounds from natural products have been of great interest in cancer chemotherapy and are currently in ...
Sepideh Mohammadhosseinpour +3 more
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, 2020 Les caspases sont une famille de cystéines protéases bien connues pour leurs rôles centraux au cours de l’apoptose et de l’inflammation. Elles interviennent aussi dans des voies de mort cellulaire régulées non-apoptotiques, et contribuent à de très ...
Étienne Jacotot, Jacotot, Étienne
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Frontiers in Physiology, 2018 Caspases are well known proteases in the context of inflammation and apoptosis. Recently, novel roles of pro-apoptotic caspases have been reported, including findings related to the development of hard tissues.
Eva Svandova +6 more
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eLife, 2017 Apoptosis and its molecular mediators, the caspases, have long been regarded as tumor suppressors and one hallmark of cancer is ‘Evading Apoptosis’.
Ernesto Pérez +2 more
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Frontiers in Neurology, 2022 ObjectiveThe interaction between the brain and lungs has been the subject of many clinical reports, while the exact impact of brain injury on the physiology of the respiratory system is still subject to numerous experimental studies.
Dorota Siwicka-Gieroba +5 more
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Journal of Neuroscience Research, 2002 AbstractThe basic mechanisms that underlie neurodegenerative diseases are unknown. Loss of function of specific regions of the brain is due to incapacitation of cells that constitute those regions. Cells can simply stop functioning normally (neurons may cease to transmit signals), or they may die.
Carol M, Troy, Guy S, Salvesen
openaire +2 more sources
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. [PDF]
, 2014 The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. An unexpected role of caspase-
Rodhe, J +11 more
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Necroptosis of Lung Epithelial Cells Triggered by Ricin Toxin and Bystander Inflammation
Cellular Physiology and Biochemistry, 2023 Background/Aims: The ribosome-inactivating proteins include the biothreat agent, ricin toxin (RT). When inhaled, RT causes near complete destruction of the lung epithelium coincident with a proinflammatory response that includes TNF family cytokines ...
LaRocca
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