Results 91 to 100 of about 9,499 (202)

A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]

, 2020
A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven, Martel, An, Martin, Charlotte, Pasmans, Frank, Raaymakers, Constantijn, Roelants, Kim, Stijlemans, Benoit, Zaman, Shabnam   +7 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Exploring the biological properties and therapeutic potential of antimicrobial peptides [PDF]

, 2014
The researchers involved in the Trans2Care project at the Department of Medical and Biological Sciences of the University of Udine investigate the biological properties of the antimicrobial peptides (AMPs) of the immune system and their therapeutic ...
D’Este, Francesca, Scarsini, Michele, Skerlavaj, Barbara, Tomasinsig, Linda, Zanetti, Margherita   +4 more
core   +1 more source

HIV Infection and Compromised Mucosal Immunity: Oral Manifestations and Systemic Inflammation [PDF]

, 2017
Mucosal surfaces account for the vast majority of HIV transmission. In adults, HIV transmission occurs mainly by vaginal and rectal routes but rarely via oral route.
Samantha E. Heron, Shokrollah Elahi
core   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Bactericidal Activity of Mammalian Cathelicidin-Derived Peptides [PDF]

Infection and Immunity, 2000
ABSTRACT Endogenous antimicrobial peptides of the cathelicidin family contribute to innate immunity. The emergence of widespread antibiotic resistance in many commonly encountered bacteria requires the search for new bactericidal agents with therapeutic potential. Solid-phase synthesis was employed to prepare linear antimicrobial
S M, Travis, N N, Anderson, W R, Forsyth, C, Espiritu, B D, Conway, E P, Greenberg, P B, McCray, R I, Lehrer, M J, Welsh, B F, Tack   +9 more
openaire   +2 more sources

Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]

, 2013
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin, Champer, Jackson, Friedman, Adam J, Kim, Jenny, Liu, Phil T, Modlin, Robert L, Oren, Ami, Phan, Jenny, Pirouz, Aslan, Qin, Min, Schairer, David O   +10 more
core   +1 more source

Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth

Maternal &Child Nutrition, EarlyView.
ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow, Rosalie Delvert, Blandine de Lauzon‐Guillain, Judith van der Waerden, Laetitia Davidovic, Olfa Khalfallah, Susana Barbosa, Marie‐Aline Charles, Cédric Galera, Barbara Heude   +9 more
wiley   +1 more source

Cathelicidins in the Tasmanian devil (Sarcophilus harrisii) [PDF]

Scientific Reports, 2016
AbstractTasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin ...
Peel, E., Cheng, Y., Djordjevic, J. T., Fox, S., Sorrell, T. C., Belov, K.   +5 more
openaire   +3 more sources

Effects of Virus-associated Molecular Patterns on the Expression of Cathelicidins in the Hen Vagina

The Journal of Poultry Science, 2016
The aim of this study was to examine the expression profiles of the cathelicidins (CATHs) in the oviduct and the effects of Toll-like receptor (TLR) ligands of virus-associated molecular patterns on CATHs expression in the vagina of hens.
Ahmad M. Abdel-Mageed, Naoki Isobe, Yukinori Yoshimura   +2 more
doaj   +1 more source