Results 31 to 40 of about 106,246 (275)

Expression of Cathepsins B, D, and G in Extracranial Arterio-Venous Malformation

Frontiers in Surgery, 2021
Objectives: We have previously identified a population of cells that expressed stemness-associated markers in extracranial arterio-venous malformation (AVM) and demonstrated expression of cathepsins B, D, and G on embryonic stem cell (ESC)-like ...
Lauren Hansen, Helen D. Brasch, Erin Paterson, Josie Patel, Nicholas Bockett, Paul F. Davis, Swee T. Tan, Swee T. Tan, Swee T. Tan   +8 more
doaj   +1 more source

Expression of Cathepsins B, D, and G in WHO Grade I Meningioma

Frontiers in Surgery, 2019
Aim: We have recently demonstrated the presence of putative tumor stem cells (TSCs) in World Health Organization (WHO) grade I meningioma (MG) localized to the microvessels, which expresses components of the renin-angiotensin system (RAS).
Rosanna M. A. Rahman, Rosanna M. A. Rahman, Bede van Schaijik, Helen D. Brasch, Reginald W. Marsh, Reginald W. Marsh, Agadha C. Wickremesekera, Agadha C. Wickremesekera, Reuben Johnson, Kelvin Woon, Swee T. Tan, Swee T. Tan, Tinte Itinteang   +12 more
doaj   +1 more source

Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]

, 2007
rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis, G. P. DILLON, H. V. ISAACS, J. C. ILLES, Pownall, R. A. WILSON, Skelly, Wilson   +7 more
core   +1 more source

Cathepsin G, a Neutrophil Protease, Induces Compact Cell-Cell Adhesion in MCF-7 Human Breast Cancer Cells

Mediators of Inflammation, 2009
Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. Because neutrophils are known to be invading leukocytes in various tumors, their products may influence the characteristics of tumor cells ...
Tomoya Kudo, Hideaki Kigoshi, Takashi Hagiwara, Takahisa Takino, Masatoshi Yamazaki, Satoru Yui   +5 more
doaj   +1 more source

IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]

, 2012
The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Bunsen, Thea, Fruth, Maximilian, Kraus, Steffen, Nägler, Dorit K.   +3 more
core   +1 more source

Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism

Mediators of Inflammation, 2014
We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity.
Satoru Yui, Yuuki Osawa, Takeo Ichisugi, Riyo Morimoto-Kamata   +3 more
doaj   +1 more source

Expression of Cathepsins B, D, and G in Isocitrate Dehydrogenase-Wildtype Glioblastoma

Frontiers in Surgery, 2017
AimTo investigate the expression of cathepsins B, D, and G, in relation to the cancer stem cell (CSC) subpopulations, we have previously characterized within isocitrate dehydogenase (IDH)-wildtype glioblastoma (IDHWGB).Methods3,3-Diaminobezidine (DAB ...
Sabrina P. Koh, Agadha C. Wickremesekera, Agadha C. Wickremesekera, Helen D. Brasch, Reginald Marsh, Swee T. Tan, Swee T. Tan, Tinte Itinteang   +7 more
doaj   +1 more source

Protective Effects of Ginger (Zingiber officinale) Extract against Diabetes-Induced Heart Abnormality in Rats [PDF]

Diabetes & Metabolism Journal, 2016
BackgroundDiabetic cardiomyopathy is an important causal factor in morbidity and mortality among diabetic patients, and currently, no effective means are available to reverse its pathological progress.
Behrouz Ilkhanizadeh, Alireza Shirpoor, Mohamad hasan Khadem Ansari, Samira Nemati, Yusef Rasmi   +4 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A., Chain, B., Deretic, V., Dockrell, D.H., Francis, S.E., Kroemer, G., Marriott, H.M., Mitchell, T.J., Read, R.C., Tulone, C., Whyte, M.K.B.   +10 more
core   +5 more sources

Targeting cathepsin G in myeloid leukemia [PDF]

OncoImmunology, 2013
Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and-aberrantly-by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute promising targets for the immunotherapy of myeloid ...
openaire   +2 more sources