Results 211 to 220 of about 51,705 (353)

CD74 and Proteases: Impact of Location on Immune and Cellular Functions. [PDF]

Cells
Dolenc I.
europepmc   +1 more source

Cathepsine [PDF]

, 2019
openaire   +1 more source

Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors

, 2006
David C. Tully, Hong Liu, Arnab K. Chatterjee, Phil B. Alper, Jennifer Williams, Michael J. Roberts, Daniel Mutnick, David H. Woodmansee, Thomas Hollenbeck, Perry Gordon, Jonathan Chang, Tove Tuntland, Christine Tumanut, Jun Li, Jennifer L. Harris, Donald S. Karanewsky   +15 more
openalex   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

Cathepsin Levels and Atrial Fibrillation Risk: Insights From Bidirectional and Multivariable Mendelian Randomization Analyses. [PDF]

Int J Genomics
Ye F, Zhou R, Lin H, Wu L, Wu X.
europepmc   +1 more source

1H-Imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: Separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka

, 2010
Wullie Arbuckle, Mark Baugh, Simone Belshaw, David Jonathan Bennett, John Bruin, Jiaqiang Cai, Kenneth S. Cameron, Chris Claxton, Maureen Dempster, Kathryn Everett, Xavier Fradera, William Hamilton, Philip S. Jones, Emma Kinghorn, Clive Long, Iain Martin, John Robinson, Paul Westwood   +17 more
openalex   +1 more source

Data from The Role of S100P in the Invasion of Pancreatic Cancer Cells Is Mediated through Cytoskeletal Changes and Regulation of Cathepsin D

, 2023
Hannah J. Whiteman, Mark E. Weeks, Sally E. Dowen, Sayka Barry, John F. Timms, Nicholas R. Lemoine, Tatjana Crnogorac‐Jurcevic   +6 more
openalex   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Comprehensive Analysis of Cathepsin Genes in Hemiptera: Functional Characterization of the Venomous Cathepsin B from Sycanus bifidus. [PDF]

Insects
Liang W, Liu S, Wang Y, Wu C, Wang W, Zhu J.   +5 more
europepmc   +1 more source

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes [PDF]

, 1991
J.F. Diedrich, Hal Minnigan, Richard I. Carp, John N. Whitaker, Richard Race, William H. Frey, Ashley T. Haase   +6 more
openalex   +1 more source