Results 101 to 110 of about 1,728 (186)

CCR6 is required for ligand-induced CatSper activation in human sperm

Oncotarget, 2017
CatSper channel has been considered the principal sperm Ca2+ channel responsible for the cytosolic Ca2+ elevation required for various sperm functions necessary for fertilization [1-4]. However, the mechanism underlying the activation of CatSper channel by various physiological ligands remain incompletely understood.
Diao, RY, Wang, T, Fok, KL, Li, XF, Ruan, YC, Yu, MK, Cheng, YM, Chen, Y, Chen, H, Mou, LS, Cai, XY, Wang, Y, Cai, ZM, Zeng, XH, Chan, HC   +14 more
openaire   +4 more sources

Expressi̇on of Catsper Δ (Delta) Channel in Human Ejaculated Sperm and Its Relati̇onshi̇p wi̇th Male Inferti̇li̇ty

, 2022
Sperm aktivasyonu ve fertilizasyon yeteneğinin kazanılmasında kalsiyum (Ca+2) iyonu oldukça önemli bir rol oynamaktadır. Catsper kanalları, Ca+2’un hücreye girişini düzenleyen, spermlere özgü voltaj kapılı Ca+2 kanallarıdır.
Kanaan, Zatelimad
core  

Network model predicts that CatSper is the main Ca2+ channel in the regulation of sea urchin sperm motility

Scientific Reports, 2017
Spermatozoa sea urchin swimming behaviour is regulated by small peptides from the egg outer envelope. Speract, such a peptide, after binding to its receptor in Strongylocentrotus purpuratus sperm flagella, triggers a signaling pathway that culminates ...
Jesús Espinal-Enríquez, Daniel Alejandro Priego-Espinosa, Alberto Darszon, Carmen Beltrán, Gustavo Martínez-Mekler   +4 more
doaj   +1 more source

Conservation of the Ca²⁺-permeability through the voltage sensor domain of mammalian CatSper subunit

, 2019
Cation channel of Spermatozoa (CatSper) is one of the voltage-gated ion channels consisting of voltage sensor domains (VSDs) and pore-gate domains. CatSper is exclusively expressed in spermatozoa and indispensable for Ca2+ influx into cytosol.
Hiroki Arima (5508302), Hidekazu Tsutsui (375493), Yasushi Okamura (268257)   +2 more
core   +1 more source

The CatSper channel is present and plays a key role in sperm motility of the Atlantic salmon (Salmo salar)

, 2021
Among all the Ca2+ channels, CatSper channels have been one of the most studied in sperm of different species due to their demonstrated role in the fertilization process. In fish sperm, the calcium channel plays a key role in sperm activation.
Herrera Belen, Lisandra, Beltran Lissabet, Jorge Felix, Risopatron, Jennie, Lee Estevez, Manuel, Farias, Jorge G., Figueroa Villalobos, Elías, Valdebenito Isler, Iván   +6 more
core  

Inhibition of the CatSper Channel and NOX5 Enzyme Activity Affects the Functions of the Progesterone-Stimulated Human Sperm

Iranian Journal of Medical Sciences, 2018
Background: Low levels of reactive oxygen species (ROS) and calcium are necessary for sperm function. NADPH oxidase 5 (NOX5) is a membrane enzyme which produces ROS. This enzyme is dependent on calcium for its activity.
Hamideh Ghanbari, Sara Keshtgar, Marjaneh Kazeroni   +2 more
doaj  

Alteration in CatSper1 and 2 genes expression, sperm parameters and testis histology in varicocelized rats

International Journal of Reproductive BioMedicine, 2018
Background: CatSper gene, a member of cation channel sperm family, has an essential role in sperm motility and male fertility. Following varicocele, sperm parameters especially sperm movement decreases.
Maryam Zohour Soleimani, Farideh Jalali Mashayekhi, Morteza Mousavi Hasanzade, Maryam Baazm   +3 more
doaj  

The systems that transport ions and their impact on sperm function and male fertility. [PDF]

Function (Oxf)
Oishee MJ, Baum B, Blanco G.
europepmc   +1 more source

CATSPERε extracellular domains are essential for sperm calcium channel assembly and activity modulation. [PDF]

Sci Adv
Hwang JY, Wang H, Oh JN, Kim J, Finnegan SF, Skakkebaek NE, Chung JJ.   +6 more
europepmc   +1 more source

CatSper channels

British Journal of Pharmacology, 2009
openaire   +2 more sources