Results 81 to 90 of about 1,915 (186)
Chromatin Protamination and Catsper Expression in Spermatozoa Predict Clinical Outcomes after Assisted Reproduction Programs [PDF]
, 2017 Identification of parameters predicting assisted reproductive technologies (ARTs) success is a major goal of research in reproduction. Quality of gametes is essential to achieve good quality embryos and increase the success of ARTs.
L. Tamburrino +16 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source
eLife, 2017 We report that the Gm7068 (CatSpere) and Tex40 (CatSperz) genes encode novel subunits of a 9-subunit CatSper ion channel complex. Targeted disruption of CatSperz reduces CatSper current and sperm rheotactic efficiency in mice, resulting in severe male ...
Jean-Ju Chung +9 more
doaj +1 more source
Advanced Science, Volume 12, Issue 44, November 27, 2025.The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu +25 more
wiley +1 more source
Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells
Frontiers in Physiology, 2020 AimExposure of boar sperm cells to Bisphenol A diglycidyl ether (BADGE) has been shown to lead to reproductive failure in sows, however, the mode of action is unknown. As we have recently shown that BADGE can interfere with Ca2 + signaling in human sperm
Anders Rehfeld +5 more
doaj +1 more source
CatSper: The complex main gate of calcium entry in mammalian spermatozoa
Molecular and Cellular Endocrinology, 2020 Calcium ions (Ca2+) are involved in nearly every aspect of cellular life. They are one of the most abundant elements in mammals and play a vital role in physiological and biochemical processes acting mainly as intracellular messengers. In spermatozoa, several key functions are regulated by cytoplasmic Ca2+ concentration such as sperm capacitation ...
Rahban, Rita, Nef, Serge
openaire +4 more sources
Molecular Reproduction and Development, Volume 92, Issue 9, September 2025.ABSTRACT The increasing focus on understanding spermatozoa mechanisms in rodents aims to enhance reproductive stability and support conservation efforts, particularly for ecologically significant and declining species like the red‐rumped agouti. We aimed to evaluate the interaction between capacitation media and time, testing BSA concentrations—low (4 ...
Lhara Ricarliany Medeiros de Oliveira +9 more
wiley +1 more source
The role of Hv1 and CatSper channels in sperm activation
The Journal of Physiology, 2010 Elevations of sperm intracellular pH and Ca(2+) regulate sperm motility, chemotaxis, capacitation and the acrosome reaction, and play a vital role in the ability of the sperm cell to reach and fertilise the egg. In human spermatozoa, the flagellar voltage-gated proton channel Hv1 is the main H(+) extrusion pathway that controls sperm intracellular pH ...
Polina V, Lishko, Yuriy, Kirichok
openaire +3 more sources
Mating system variation and gene expression in the male reproductive tract of Peromyscus mice
Molecular Ecology, Volume 34, Issue 15, August 2025.Abstract Genes involved in reproduction often evolve rapidly at the sequence level due to postcopulatory sexual selection (PCSS) driven by male–male competition and male–female sexual conflict, but the impact of PCSS on gene expression has been under‐explored.
Erin R. Voss, Michael W. Nachman
wiley +1 more source
Asymmetrically Positioned Flagellar Control Units Regulate Human Sperm Rotation
Cell Reports, 2018 Summary: Ion channels control sperm navigation within the female reproductive tract and, thus, are critical for their ability to find and fertilize an egg.
Melissa R. Miller +8 more
doaj +1 more source