Results 51 to 60 of about 1,915 (186)
Reproductive Biology and Endocrinology, 2011 Background Sperm ion channel proteins (CatSpers) are essential for sperm hyperactivated motility, and then penetration through the zona pellucida. The CatSper class of proteins have well been characterized in the mouse and human.
Li Bichun +7 more
doaj +1 more source
Redox Biology, 2021 To fertilize an oocyte, sperm must undergo several biochemical and functional changes known as capacitation. A key event in capacitation is calcium influx through the cation channel of sperm (CatSper).
Juan J. Ferreira +8 more
doaj +1 more source
Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm
Frontiers in Cell and Developmental Biology, 2020 Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper.
Melanie Balbach +14 more
doaj +1 more source
Effects of Fscb/Cabyr double gene knockout on reproductive capacity in male mice
Di-san junyi daxue xuebao, 2021 Objective To evaluate the value of CABYR protein and its complex with FSCB in maintaining sperm fertilization ability and investigate the possible mechanism of physiological function of the coruplex by observing the natural fertility of Fscb/Cabyr double
LI Zhongtai +6 more
doaj +1 more source
Pimozide Inhibits CatSper Activity, Impairs Hyperactivation and the Acrosome Reaction in Human Spermatozoa [PDF]
Int J Mol SciHealth, social, and ethical considerations highlight the need for new male contraceptives. Pimozide is an FDA approved drug known to block T-type calcium channels and which shares structural similarities with mibefradil, a proven antagonist of the ...
Torres Juárez J +4 more
europepmc +2 more sources
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Estudio de la activación del canal de calcio CatSper en espermatozoides ovinos [PDF]
, 2022 El calcio es un catión que actúa como agente señalizador fundamental para que los espermatozoides adquieran capacidad fecundante, dado que participa en los procesos de capacitación, hiperactivación, quimiotaxis y reacción acrosómica.
Brú Albesa, Marcos +2 more
core
, 2023 The sperm-specific channel CatSper (cation channel of sperm) controls the intracellular Ca2+ concentration ([Ca2+]i) and plays an essential role in sperm function.
Francesco Luigi Gervasio (1357401) +9 more
core +1 more source
Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function
Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez +3 more
wiley +1 more source
Expression of Sperm-specific Cation Channel CatSper in Human Spermatozoa [PDF]
, 2004 PURPOSE: We aimed to elucidate the expression and intracellular localization of sperm-specific cation channel CatSper in human spermatozoa. Moreover, the relationship between the expression of CatSper mRNA and the motility of ejaculated human spermatozoa
최형기
core