Results 51 to 60 of about 1,728 (186)

Effects of Fscb/Cabyr double gene knockout on reproductive capacity in male mice

Di-san junyi daxue xuebao, 2021
Objective To evaluate the value of CABYR protein and its complex with FSCB in maintaining sperm fertilization ability and investigate the possible mechanism of physiological function of the coruplex by observing the natural fertility of Fscb/Cabyr double
LI Zhongtai, LI Zhongtai, LI Yanfeng, LIU Jinyi, ZHANG Yong, ZHANG Jun, BI Gang   +6 more
doaj   +1 more source

Investigation of the effect of diazinon on CatSper 1 gene expression, sperm motility and germinal epithelium thickness in adult male mice [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: Genetic changes and mutations in the genes involved in spermatogenesis can occur by environmental and congenital factors. Considering, the extensive use of diazinon in the farms and because we found no study on the effects of diazinon
hamid reza faragnezhad, shabnam mohammadi, seyed morteza Seifati, atena mansouri, reyhaneh mahmoodian   +4 more
doaj   +1 more source

Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm

Frontiers in Cell and Developmental Biology, 2020
Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper.
Melanie Balbach, Hussein Hamzeh, Jan F. Jikeli, Christoph Brenker, Christian Schiffer, Jan N. Hansen, Pia Neugebauer, Christian Trötschel, Luca Jovine, Ling Han, Harvey M. Florman, U. Benjamin Kaupp, U. Benjamin Kaupp, Timo Strünker, Dagmar Wachten   +14 more
doaj   +1 more source

Transmission Ratio Distortion Detection Using Microsatellite and Single Nucleotide Polymorphism Markers in Hanwoo of Gyeongnam Province

Animal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT This study aimed to identify and compare transmission ratio distortion (TRD) patterns using microsatellite (MS) markers and single nucleotide polymorphism (SNP) markers in a Hanwoo population from Gyeongnam Province. The objective was to construct parent‐offspring trios and investigate TRD patterns that may influence mortality and economic ...
Ji‐Yeong Kim, Ho‐Chan Kang, Cheol‐Hyun Myung, Hyun‐Tae Lim   +3 more
wiley   +1 more source

Expression of Sperm-specific Cation Channel CatSper in Human Spermatozoa [PDF]

, 2004
PURPOSE: We aimed to elucidate the expression and intracellular localization of sperm-specific cation channel CatSper in human spermatozoa. Moreover, the relationship between the expression of CatSper mRNA and the motility of ejaculated human spermatozoa
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core  

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, Volume 14, Issue 3, Page 747-765, March 2026.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Calpain‐1 and Cholesterol Regulate the Dynamics of the Lipid Membrane Domains Essential for Suitable Capacitation and Acrosomal Reactions

Journal of Cellular Physiology, Volume 241, Issue 2, February 2026.
The role of calpain‐1 and cholesterol during capacitation. The activation of calpain‐1 and cholesterol redistribution directs distinct events involved in capacitation, including the degradation of the spectrin cytoskeleton, protein phosphorylation at Tyr, actin polymerization, lipid rafts remodeling, and calcium influx, among others. ABSTRACT Calpain‐1
Aide A. Muñoz‐Sánchez, Monica L. Salgado‐Lucio, Coral Y. Jorge‐Cruz, Ana L. Roa‐Espitia, Rafael Baltiérrez‐Hoyos, Enrique O. Hernández‐González   +5 more
wiley   +1 more source

Estudio de la activación del canal de calcio CatSper en espermatozoides ovinos [PDF]

, 2022
El calcio es un catión que actúa como agente señalizador fundamental para que los espermatozoides adquieran capacidad fecundante, dado que participa en los procesos de capacitación, hiperactivación, quimiotaxis y reacción acrosómica.
Brú Albesa, Marcos, Pérez Pé, Rosaura, Miguel Jiménez, Sara   +2 more
core  

Deciphering mRNA Translation During Sperm Capacitation: A New Frontier in Fertility Research

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Male infertility accounts for approximately 50% of infertility cases, with nearly 30% remaining unexplained after standard evaluations. This highlights the need for a better understanding of sperm function to advance diagnostic and therapeutic strategies. Sperm were long considered translationally quiescent; however, emerging evidence suggests
Saurabh Tiwari, Nehal Thakor, Jacob Thundathil   +2 more
wiley   +1 more source

DataSheet1_The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm.docx

, 2023
The sperm-specific channel CatSper (cation channel of sperm) controls the intracellular Ca2+ concentration ([Ca2+]i) and plays an essential role in sperm function.
Francesco Luigi Gervasio (1357401), Ioannis Galdadas (16620288), Stéphane Guerrier (4480117), Lydia Wehrli (16620285), Martin Smieško (4027895), Yves Cambet (2677162), Lionel Voirol (11936155), Vincent Jaquet (4823994), Rita Rahban (3639253), Serge Nef (45552)   +9 more
core   +1 more source