Results 1 to 10 of about 44,977 (257)

Endocytosis Via Caveolae [PDF]

Traffic, 2002
Caveolae are flask‐shaped invaginations present in the plasma membrane of many cell types. They have long been implicated in endocytosis, transcytosis, and cell signaling. Recent work has confirmed that caveolae are directly involved in the internalization of membrane components (glycosphingolipids and glycosylphosphatidylinositol‐anchored proteins ...
Ari Helenius
exaly   +5 more sources

Pathophysiological Role of Caveolae in Hypertension [PDF]

Frontiers in Medicine, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver, Gollasch, Maik, Kaßmann, Mario, Lian, Xiaoming, Matthaeus, Claudia   +4 more
core   +6 more sources

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells [PDF]

Nature Communications, 2019
Caveolin-3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene cause different types of myopathies with altered membrane integrity and repair, expression of muscle proteins, and regulation of signaling pathways. We show here
Darius Vasco Köster, Bidisha Sinha, anne Bigot   +2 more
exaly   +6 more sources

Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B [PDF]

, 2015
Voltage-gated potassium channels (Kv) are important regulators of membrane potential in vascular smooth muscle cells, which is integral to controlling intracellular Ca2+ concentration and regulating vascular tone. Previous work indicates that Kv channels
A Adebiyi, A Cheong, A Cogolludo, A Moreno-Dominguez, AJ Wilson, AM Brainard, B Kyle, B Razani, B Razani, C Dart, C Dart, Carl P. Nelson, CL Moore, CP Nelson, CP Nelson, DP McEwen, DW Carr, EA Aiello, EA Aiello, EA Ko, EA Ko, F Plane, GC Wellman, GI Purves, H Li, H Miyoshi, HS Mason, IA Greenwood, J Couet, J Moral-Sanz, JB Stott, JD Scott, JD Turner, Jennifer L. Brignell, JM Quayle, Jonathon M. Willets, JR Martens, KD Luykenaar, KS Park, LF Santana, LJ Sampson, LM Davies, M Colledge, Mark S. Shapiro, Matthew D. Perry, MF Navedo, MG Gold, MT Nelson, NM Alto, NN Orie, Noel W. Davies, O Clement-Chomienne, P Skroblin, R. A. John Challiss, RD Rainbow, RD Rainbow, RD Rainbow, RH Cox, RT Dobrowsky, SA Barman, VM Coghlan, Y Hayabuchi, Y Hayabuchi, Y Hayabuchi, Y Yang   +64 more
core   +6 more sources

Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]

, 2019
Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Dobrow, Sebastian, Flores, Claudia, Linden, Jennifer R, Michel, Adam O, Schmidt, Eric F, Uzal, Francisco A, Valenzuela, Marissa, Vartanian, Timothy   +7 more
core   +1 more source

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]

, 2001
Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH, Kanzaki, M, Macara, IG, Mora, S, Pessin, JE, Saltiel, AR, Shigematsu, S, Watson, RT   +7 more
core   +3 more sources

Selective Cholesterol Dynamics between Lipoproteins and Caveolae/Lipid Rafts [PDF]

, 2007
Although low-density lipoprotein (LDL) receptor-mediated cholesterol uptake through clathrin-coated pits is now well understood, the molecular details and organizing principles for selective cholesterol uptake/efflux (reverse cholesterol transport, RCT ...
Atshaves, Barbara P., Ball, Judith M., Gallegos, Adalberto M., Kier, Ann B., Landrock, Kerstin K., Martin, Gregory G., McIntosh, Avery L., Parr, Rebecca D., Schroeder, Friedhelm, Storey, Stephen M.   +9 more
core   +2 more sources

Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation [PDF]

, 2017
Caveolae are signal transduction centers, yet their subcellular distribution and preservation in cardiac myocytes after cell isolation are not well documented.
Alexander D. Corbett, Andreas Hoenger, Aravamudan, Baczkó, Balijepalli, Balijepalli, Bozzola, Brette, Bub, Bősze, Calaghan, Calaghan, Carozzi, Cheng, Di Maio, Drab, Dulhunty, Eva A. Rog-Zielinska, Forbes, Galbiati, Galiñanes, Gil Bub, Golowasch, Groulx, Hagiwara, Hansen, Harken, Harvey, Hayashi, Head, Hong, Ilona Bodi, Iribe, Ishikawa, Jayasinghe, Judith Sheldon, Jung, Karnovsky, Kawamura, Kohl, Kong, Kozera, Kremer, Levin, Liu, Louch, Löhn, Macdougall, Maguy, Martin Fink, Mastronarde, Mitcheson, Mitcheson, Mundy, Murata, Nerbonne, Ostrom, Palade, Panfilov, Parton, Parton, Pavlović, Pelkmans, Pelkmans, Pelkmans, Peter Kohl, Peyronnet, Pfeiffer, Quinn, Razani, Rebecca A.B. Burton, Rog-Zielinska, Rothberg, Rybin, Rémi Peyronnet, Sarah C. Calaghan, Savio-Galimberti, Scardigli, Scherer, Scriven, Sens, Serna, Simons, Sinha, Song, Stahlhut, Stan, Steinberg, Sun, Tang, Trump, Valentin, Wagner, Way, Wong, Woodman, Wright, Yaniv   +97 more
core   +2 more sources

Nanoplastics: From tissue accumulation to cell translocation into Mytilus galloprovincialis hemocytes. resilience of immune cells exposed to nanoplastics and nanoplastics plus Vibrio splendidus combination [PDF]

, 2020
Plastic litter is an issue of global concern. In this work Mytilus galloprovincialis was used to study the distribution and effects of polystyrene nanoplastics (PS NPs) of different sizes (50 nm, 100 nm and 1 mu m) on immune cells.
Figueras, A., Novoa, B., Romero, A., Saco, A., Sendra, M., Yeste Sigüenza, María del Pilar   +5 more
core   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +6 more sources