Results 121 to 130 of about 44,977 (257)

Annexin A1‐Targeted d‐Peptide‐Monomethyl Auristatin E Conjugate Enhanced Antitumor Effect of Monomethyl Auristatin E for Chemotherapy of Prostate Cancer

open access: yesThe Prostate, Volume 85, Issue 13, Page 1208-1221, September 15, 2025.
ABSTRACT Background N‐terminus 15 amino acid (MC16) of Annexin A1 (ANXA1) is an effective therapeutic target for tumors and tumor vasculature as it specifically localizes to the cell surface of tumor cells and tumor vascular endothelial cells. We identified the d‐type peptide (hpnevrs, dhp7) by mirror‐image phage display targeting l‐type MC16 and ...
Kai Ozaki   +8 more
wiley   +1 more source

Activated Protein Kinase C Isoforms Target to Cardiomyocyte Caveolae

open access: bronze, 1999
Vitalyi O. Rybin   +2 more
openalex   +1 more source

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

open access: yesInternational Journal of Cancer, Volume 157, Issue 4, Page 788-799, 15 August 2025.
What's new? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini   +18 more
wiley   +1 more source

PC12 Cells Have Caveolae That Contain TrkA [PDF]

open access: hybrid, 2000
Sandra Peiró   +4 more
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, Volume 15, Issue 8, Page 1350-1364, August 2025.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

Dystrophin Associates With Caveolae of Rat Cardiac Myocytes [PDF]

open access: bronze, 2000
Donald D. Doyle   +6 more
openalex   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

open access: yesAdvanced Science, Volume 12, Issue 31, August 21, 2025.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li   +11 more
wiley   +1 more source

Interrelationship Between Intraepithelial Nerve Endings and Epithelial Cells in the Rat Epiglottis Revealed by Array Tomography With Scanning Electron Microscopy

open access: yesJournal of Comparative Neurology, Volume 533, Issue 8, August 2025.
Two types of intraepithelial nerve endings were observed in the epiglottis, i.e., thin nerve fibers/endings with varicosities and terminal swelling and ramified nerve ending consisted of a branched parent axon and large terminal parts. Both nerve endings were closely attached with epithelial cells.
Yoshio Yamamoto   +4 more
wiley   +1 more source

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