Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae [PDF]
Hong Ju+5 more
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Forty‐five components of WSEE were identified by UPLC‐Q‐TOF‐MS. The main targets of WSEE were PTPN2, ADRB2, LTA4H, and so on in wound healing. WSEE has an anti‐inflammatory effect in LPS‐stimulated RAW264.7 cells, procoagulant activity in vitro, and shortens hemostasis time in vivo.
Ying He+9 more
wiley +1 more source
A Chimeric Transmembrane Domain Directs Endothelial Nitric-oxide Synthase Palmitoylation and Targeting to Plasmalemmal Caveolae [PDF]
Prakash Prabhakar+2 more
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Presence of Oxidized Cholesterol in Caveolae Uncouples Active Platelet-derived Growth Factor Receptors from Tyrosine Kinase Substrates [PDF]
Pingsheng Liu+4 more
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Extracellular vesicles from Limosilactobacillus johnsonii reach the mammary gland through the gut‐mammary axis, where their palmitic acid (C16:0) induce the dynamic changes in CD36 palmitoylation in mammary epithelial cells, thereby facilitating fatty acid uptake as substrates and enhance milk fat synthesis in HC11 cells via PPARγ signalling.
Qihui Li+8 more
wiley +1 more source
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]
Gross, Richard W.+4 more
core +2 more sources
Proteomic and miRNAseq analyses of exosomes derived from early passage (non‐senescent) versus senescent human coronary artery endothelial cells derived from the same donor indicate that senescence changed the protein and miRNA content of shed exosomes towards a more pro‐inflammatory profile.
Ryan E. Hogans+8 more
wiley +1 more source
Alteration of plasmalemmal caveolae mimics endothelial dysfunction observed in atheromatous rabbit aorta [PDF]
B. Darblade
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ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth+2 more
wiley +1 more source
Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control [PDF]
Santiago Parpal+3 more
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