Results 11 to 20 of about 44,977 (257)
Regulated internalization of caveolae [PDF]
The Journal of cell biology, 1994 Caveolae are specialized invaginations of the plasma membrane which have been proposed to play a role in diverse cellular processes such as endocytosis and signal transduction.
Joggerst, B., Parton, R. G., Simons, K.
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Current Biology, 2018 Caveolae are one of the most abundant and striking features of the plasma membrane of many mammalian cell types. These surface pits have fascinated biologists since their discovery by the pioneers of electron microscopy in the middle of the last century, but we are only just starting to understand their multiple functions.
Parton, Robert G +2 more
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Traffic, 2019 AbstractCaveolae are an abundant, but enigmatic, plasma membrane feature of vertebrate cells. In this brief commentary, the authors attempt to answer some key questions related to the formation and function of caveolae based on round‐table discussions at the first EMBO Workshop on Caveolae held in France in May 2019.
Parton, Robert +10 more
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Journal of Cell Science, 2010 The plasma membrane is more than a simple delimitation of the boundary of the cell but is a dynamic multi-domain membrane system participating in numerous cellular processes. In many different cell types, the plasma membrane is heavily decorated with small pits of 60–80 nm in diameter ...
Bastiani, M, Parton, RG
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Caveolae: biochemical analysis [PDF]
Molecular Biology Reports, 2004 Caveolae appear in a multitude of processes encompassing growth regulation and trafficking. We demonstrate the abundant presence of ESA/reggie-1/flotillin-2, ATP synthase beta subunit and annexin V in endothelial caveolae by immunopurification of caveolae from vascular endothelial membrane.
Klaus Fiedler +5 more
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Glycolipid‐Enriched Caveolae and Caveolae‐Like Domains in the Nervous System [PDF]
Journal of Neurochemistry, 1999 Abstract: Recent years have been characterized by a booming interest in research on caveolae and caveolae‐like membrane domains. The interest in this subject grew further, when their involvement in fundamental membrane‐associated events, such as signal transmission and lipid/protein sorting, was postulated.
MASSERINI, MASSIMO ERNESTO +2 more
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Revolutionizing Autoimmune Research: The Role of Caveolin-1. [PDF]
Immun Inflamm DisABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Gao Y +8 more
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Caveolae structure and function [PDF]
Journal of Cellular and Molecular Medicine, 2008 Studies on the structure and function of caveolae have revealed how this versatile subcellular organelle can influence numerous signalling pathways. This brief review will discuss a few of the key features of caveolae as it relates to signalling and disease processes.
Candice M. Thomas, Eric J. Smart
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Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]
, 2016 RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica +15 more
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Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
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