Results 31 to 40 of about 60,250 (276)

Niemann-Pick C1 protein regulates cholesterol transport to the trans-Golgi network and plasma membrane caveolae

Journal of Lipid Research, 2002
The Niemann-Pick C1 (NPC1) protein regulates cholesterol transport from late endosomes-lysosomes to other intracellular compartments. In this article, cholesterol transport to caveolin-1 and caveolin-2 containing compartments, such as the trans-Golgi ...
William S. Garver, Kumar Krishnan, Jayme R. Gallagos, Makoto Michikawa, Gordon A. Francis, Randall A. Heidenreich   +5 more
doaj   +1 more source

Prognostic significance of epithelial/stromal caveolin‐1 expression in prostatic hyperplasia, high grade prostatic intraepithelial hyperplasia and prostatic carcinoma and its correlation with microvessel density

Journal of the Egyptian National Cancer Institute, 2017
Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj   +1 more source

Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]

, 2014
The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V., Chodosh, James, Lee, Jeong Yoon, Mukherjee, Santanu, Rajaiya, Jaya, Ramke, Mirja, Yousuf, Mohammad A., Zhou, Xiaohong   +7 more
core   +1 more source

A New N-terminal Recognition Domain in Caveolin-1 Interacts with Sterol Carrier Protein-2 (SCP-2) [PDF]

, 2007
Although plasma membrane domains, such as caveolae, provide an organizing principle for signaling pathways and cholesterol homeostasis in the cell, relatively little is known regarding specific mechanisms, whereby intracellular lipid-binding proteins are
Ball, Judith M., Hostetler, Heather A., Kier, Ann B., Martin, Gregory G., Mir, Kiran D., Parr, Rebecca D., Schroeder, Friedhelm, Schroeder, Megan E.   +7 more
core   +2 more sources

Redox Regulation of Signaling Complex between Caveolin-1 and Neuronal Calcium Sensor Recoverin

Biomolecules, 2022
Caveolin-1 is a cholesterol-binding scaffold protein, which is localized in detergent-resistant membrane (DRM) rafts and interacts with components of signal transduction systems, including visual cascade.
Vasiliy I. Vladimirov, Margarita P. Shchannikova, Alexey V. Baldin, Alexey S. Kazakov, Marina P. Shevelyova, Aliya A. Nazipova, Viktoriia E. Baksheeva, Ekaterina L. Nemashkalova, Anastasia S. Frolova, Natalia K. Tikhomirova, Pavel P. Philippov, Andrey A. Zamyatnin, Sergei E. Permyakov, Dmitry V. Zinchenko, Evgeni Yu. Zernii   +14 more
doaj   +1 more source

The Rotavirus Enterotoxin NSP4 Directly Interacts with the Caveolar Structural Protein Caveolin-1 [PDF]

, 2006
Rotavirus nonstructural protein 4 (NSP4) is known to function as an intracellular receptor at the endoplasmic reticulum (ER) critical to viral morphogenesis and is the first characterized viral enterotoxin.
Ball, Judith M., McIntosh, Avery, Mir, Kiran D., Mitchell, DeAnne M., Parr, Rebecca D., Storey, Stephen M., Zhou, Minglong   +6 more
core   +2 more sources

Caveolin-1-dependent and -independent membrane domains [PDF]

Journal of Lipid Research, 2009
Lipid rafts defined as cholesterol- and sphingomyelin-rich domains have been isolated from different cell types that vary greatly in their lipid profiles. Here, we investigated the contribution of the structural protein caveolin-1 (Cav1) to the overall lipid composition and domain abundance in mouse embryonic fibroblasts (MEFs) from wild-type (WT) or ...
Le Lay, Soazig, Li, Qiong, Proschogo, Nicholas, Rodriguez, Macarena, Gunaratnam, Krishanthi, Cartland, Siân, Rentero, Carles, Jessup, Wendy, Mitchell, Todd, Gaus, Katharina   +9 more
openaire   +5 more sources

Involvement of caveolin-1 in skin diseases

Frontiers in Immunology, 2022
The skin is the outermost layer and largest organ in the human body. Since the skin interfaces with the environment, it has a variety of roles, including providing a protective barrier against external factors, regulating body temperature, and retaining water in the body.
Naoko Takamura, Yukie Yamaguchi
openaire   +3 more sources

Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension

Scientific Reports, 2017
Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through their deformation. Few quantitative studies on the deformation of caveolae have been reported.
Masashi Tachikawa, Nobuhiro Morone, Yosuke Senju, Tadao Sugiura, Kyoko Hanawa-Suetsugu, Atsushi Mochizuki, Shiro Suetsugu   +6 more
doaj   +1 more source

Caveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases

Indian Journal of Dermatology, 2014
Background: Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by
Feng Zhang, Heyu Li, Yicheng Zhou, Yunhe Gu, Lifeng Wang   +4 more
doaj   +1 more source