Results 41 to 50 of about 60,250 (276)
Caveolin-1 is involved in fatty infiltration and bone-tendon healing of rotator cuff tear
Molecular Medicine, 2023 Background Caveolin-1 has been predicted, based on RNA transcriptome sequencing, as a key gene in rotator cuff tear (RCT) and it is related to fatty infiltration.
Shanhong Fang +3 more
doaj +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
, 2010 The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V. +2 more
core +2 more sources
Tumor Biology, 2017 Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non–small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cells is still ...
Eleonora Duregon +8 more
doaj +1 more source
Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension
Medical Sciences, 2021 Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH.
Rajamma Mathew
doaj +1 more source
Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. [PDF]
PLoS ONE, 2013 A multiplicity of vital cellular and tissue level functions are controlled by caveolin-1 and it is considered to be an important candidate for targeted therapeutics.
Min Shao +5 more
doaj +1 more source
Pathophysiological Role of Caveolae in Hypertension [PDF]
, 2019 Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver +4 more
core +2 more sources
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
BMC Cancer, 2012 Background To understand the molecular mechanisms of caveolin-1 downregulation by hepatitis B virus X protein (HBx). Methods The DNA methylation status of the caveolin-1 promoter was examined by nested methylation-specific PCR of 33 hepatitis B virus ...
Yan Jun +5 more
doaj +1 more source
Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]
, 2014 Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L +11 more
core +2 more sources
Dermatologica Sinica, 2018 Background: Caveolin-1 (CAV-1) is a key structural and functional membrane protein that is thought to play a role in controlling cellular proliferation and differentiation. Objective: To study the immunohistochemical expression of caveolin-1 in psoriasis
Shereen Farouk Gheida +2 more
doaj +1 more source