Results 21 to 30 of about 4,498 (153)

CCL24 Protects Renal Function by Controlling Inflammation in Podocytes [PDF]

Disease Markers, 2021
Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with chronic inflammation. We have examined the role of the inflammatory chemokine CCL24 in DN. We observed that serum levels of CCL24 were significantly elevated in patients with DN.
Youdi Wang, Xue Wu, Mengya Geng, Jiamin Ding, Kangjia Lv, Hui Du, Jiahui Ding, Wenjun Pei, Xin Hu, Jing Gu, Lizhuo Wang, Yao Zhang, Jialin Gao   +12 more
openaire   +2 more sources

When Resident Macrophages Call, Fibroblasts Answer: CCL24-CCR3 in Fibrosis. [PDF]

Circ Res
Bayer AL, Alcaide P.
europepmc   +4 more sources

Macrophage-Derived CCL24 Promotes Cardiac Fibrosis Via Fibroblast CCR3. [PDF]

Circ Res
BACKGROUND: Inflammation is a significant risk factor and contributor to the development of cardiovascular disease by driving adaptive and maladaptive responses to cardiac injury. Macrophages are the most abundant immune cells in the heart and play an important role in the remodeling of cardiac tissue.
Parthiban P, Barrow F, Wang H, Chalise U, Araujo N, Souza-Neto F, Nguyen H, Draxler M, Pallais JP, Yucel D, Liu H, Ciske E, Fehrenbach P, Hakeem A, Lee SH, Herman A, Rothenberg ME, Dudley S, van Berlo JH, Revelo XS.   +19 more
europepmc   +3 more sources

Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis [PDF]

Communications Biology, 2020
AbstractSarcoidosis is a genetically complex systemic inflammatory disease that affects multiple organs. We present a GWAS of a Japanese cohort (700 sarcoidosis cases and 886 controls) with replication in independent samples from Japan (931 cases and 1,042 controls) and the Czech Republic (265 cases and 264 controls).
Akira Meguro, Mami Ishihara, Martin Petrek, Ken Yamamoto, Masaki Takeuchi, Frantisek Mrazek, Vitezslav Kolek, Alzbeta Benicka, Takahiro Yamane, Etsuko Shibuya, Atsushi Yoshino, Akiko Isomoto, Masao Ota, Keisuke Yatsu, Noriharu Shijubo, Sonoko Nagai, Etsuro Yamaguchi, Tetsuo Yamaguchi, Kenichi Namba, Toshikatsu Kaburaki, Hiroshi Takase, Shin-ichiro Morimoto, Junko Hori, Keiko Kono, Hiroshi Goto, Takafumi Suda, Soichiro Ikushima, Yasutaka Ando, Shinobu Takenaka, Masaru Takeuchi, Takenosuke Yuasa, Katsunori Sugisaki, Nobuyuki Ohguro, Miki Hiraoka, Nobuyoshi Kitaichi, Yukihiko Sugiyama, Nobuyuki Horita, Yuri Asukata, Tatsukata Kawagoe, Ikuko Kimura, Mizuho Ishido, Hidetoshi Inoko, Manabu Mochizuki, Shigeaki Ohno, Seiamak Bahram, Elaine F. Remmers, Daniel L. Kastner, Nobuhisa Mizuki   +47 more
openaire   +3 more sources

Single-Cell RNA-Seq Reveals a Crosstalk between Hyaluronan Receptor LYVE-1-Expressing Macrophages and Vascular Smooth Muscle Cells

Cells, 2022
Background: Atherosclerosis is a chronic inflammatory disease where macrophages participate in the progression of the disease. However, the role of resident-like macrophages (res-like) in the atherosclerotic aorta is not completely understood. Methods: A
Fabienne Burger, Daniela Baptista, Aline Roth, Karim J. Brandt, Rafaela Fernandes da Silva, Fabrizio Montecucco, François Mach, Kapka Miteva   +7 more
doaj   +1 more source

Endothelial and Epithelial Expression of Eotaxin-2 (CCL24) in Nasal Polyps [PDF]

International Archives of Allergy and Immunology, 2006
<i>Background:</i> Nasal polyposis is mostly associated with eosinophilia of mucosal tissue. This points to the implication of CC chemokines in nasal eosinophilia. Recently the CC chemokine eotaxin-2 (CCL24) was identified. This study was initiated to localize the cellular source, analyze expression of mRNA, and quantify protein synthesis ...
Schäfer, D., Meyer, J. E., Pods, R., Pethe, W., Hedderich, J., Schmidt, C., Maune, S.   +6 more
openaire   +3 more sources

Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis

Nature Communications, 2023
Tissue-resident macrophages are critical for tissue homeostasis and repair. We previously showed that dermis-resident macrophages produce CCL24 which mediates their interaction with IL-4+ eosinophils, required to maintain their M2-like properties in the ...
Sang Hun Lee, Byunghyun Kang, Olena Kamenyeva, Tiago Rodrigues Ferreira, Kyoungin Cho, Jaspal S. Khillan, Juraj Kabat, Brian L. Kelsall, David L. Sacks   +8 more
doaj   +1 more source

EBF3 suppresses lung adenocarcinoma progression and immune evasion via transcriptional repression of CCL24. [PDF]

Cell Oncol (Dordr)
Li L, Yang Y, Li D, Chen C, Mu X, Wu J, Yuan J.   +6 more
europepmc   +2 more sources

Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)

Frontiers in Pharmacology, 2023
Atypical chemokine receptors (ACKRs) play pivotal roles in immune regulation by binding chemokines and regulating their spatial distribution without inducing G-protein activation.
Remy Bonnavion, Remy Bonnavion, Shangmin Liu, Haruya Kawase, Kenneth Anthony Roquid, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns   +8 more
doaj   +1 more source

Downregulation of Salt-Inducible Kinase 3 Enhances CCL24 Activation in the Placental Environment with Preeclampsia

International Journal of Molecular Sciences, 2023
Preeclampsia (PE) remains one of the leading causes of maternal and perinatal morbidity and mortality. However, the exact pathophysiology of PE is still unclear. The recent widely accepted notion that successful pregnancy relies on maternal immunological adaptation is of utmost importance.
Hsing-Fen Tsai, Ching-Fen Tseng, Yu-Ling Liang, Pei-Ying Wu, Lan-Yin Huang, Yu-Han Lin, Li-Hsuan Lin, Chang-Ni Lin, Keng-Fu Hsu   +8 more
openaire   +2 more sources