Results 31 to 40 of about 4,498 (153)

Interleukin‐13 directly promotes oesophagus production of CCL11 and CCL24 and the migration of eosinophils [PDF]

Clinical & Experimental Allergy, 2010
SummaryBackground Eosinophilic oesophagitis (EE) is a clinico‐pathologically defined oesophageal disorder that is characterized by eosinophil migration into oesophageal tissues. There is growing support for EE being an allergic disease and for a contribution of T‐helper type 2 (Th2)‐associated cytokines in disease pathogenesis.
C V, Neilsen, P J, Bryce
openaire   +2 more sources

Integration of single-cell sequencing and bulk expression data reveals chemokine signaling pathway in proliferating cells is associated with the survival outcome of osteosarcoma

BMC Medical Genomics, 2023
Background Osteosarcoma, as the most common primary bone malignancy, is urgent to be well-studied on the biomarkers and therapeutic targets to improve the five-year survival rate.
Lin Yu, Sun Hongyu, Chen Yuxi
doaj   +1 more source

IL-22BP production is heterogeneously distributed in Crohn’s disease

Frontiers in Immunology, 2022
Crohn’s disease (CD), a form of inflammatory bowel disease (IBD), is characterized by impaired epithelial barrier functions and dysregulated mucosal immune responses.
Aurélie Fantou, Aurélie Fantou, Eric Lagrue, Thomas Laurent, Laurence Delbos, Stéphanie Blandin, Anne Jarry, Gaëlle Beriou, Cécile Braudeau, Cécile Braudeau, Nina Salabert, Nina Salabert, Eros Marin, Aurélie Moreau, Juliette Podevin, Arnaud Bourreille, Régis Josien, Régis Josien, Jérôme C. Martin, Jérôme C. Martin   +19 more
doaj   +1 more source

Clinical Usefulness of Monitoring Expression Levels of CCL24 (Eotaxin-2) mRNA on the Ocular Surface in Patients with Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis

Journal of Ophthalmology, 2016
Purpose. This study aimed to evaluate the clinical efficacy of using expression levels of CCL24 (eotaxin-2) mRNA on the ocular surface as a biomarker in patients with vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC).
Yukiko Shiraki, Jun Shoji, Noriko Inada
doaj   +1 more source

Natural Killer Receptor 1 Dampens the Development of Allergic Eosinophilic Airway Inflammation. [PDF]

PLoS ONE, 2016
The function of NCR1 was studied in a model of experimental asthma, classified as a type 1 hypersensitivity reaction, in mice. IgE levels were significantly increased in the serum of OVA immunized NCR1 deficient (NCR1gfp/gfp) mice in comparison to OVA ...
Shirin Elhaik Goldman, Itay Moshkovits, Avishai Shemesh, Ayelet Filiba, Yevgeny Tsirulsky, Elena Vronov, Marilou Shagan, Ron N Apte, D Aniel Benharroch, Danielle Karo-Atar, Ron Dagan, Ariel Munitz, Yaffa Mizrachi Nebenzahl, Angel Porgador   +13 more
doaj   +1 more source

Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity

Scientific Reports, 2017
Microbiota maintains host tissue homeostasis and influences tissue-resident macrophages. However, the mechanisms by which commensal bacteria in regulating the alveolar macrophages remain unclear. Here, by using an antibiotic-treated (Abt) mouse model, we
Min Cheng, Yongyan Chen, Liang Wang, Wen Chen, Ling Yang, Guodong Shen, Tingjuan Xu, Gan Shen, Zhigang Tian, Shilian Hu   +9 more
doaj   +1 more source

Higher expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 chemokines in the skin associated with parasite density in canine visceral leishmaniasis. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: The immune response in the skin of dogs infected with Leishmania infantum is poorly understood, and limited studies have described the immunopathological profile with regard to distinct levels of tissue parasitism and the clinical progression
Daniel Menezes-Souza, Renata Guerra-Sá, Cláudia Martins Carneiro, Juliana Vitoriano-Souza, Rodolfo Cordeiro Giunchetti, Andréa Teixeira-Carvalho, Denise Silveira-Lemos, Guilherme Corrêa Oliveira, Rodrigo Corrêa-Oliveira, Alexandre Barbosa Reis   +9 more
doaj   +1 more source

Establishing Classification Tree Models in Rheumatoid Arthritis Using Combination of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Magnetic Beads

Frontiers in Medicine, 2021
Background: There is no simple method for early diagnosis and evaluation of rheumatoid arthritis (RA). This study aimed to determine potential biomarkers and establish diagnostic patterns for RA using proteomic fingerprint technology combined with ...
Dan Ma, Nana Liang, Liyun Zhang
doaj   +1 more source

Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni

Memorias do Instituto Oswaldo Cruz, 2010
The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis.
Denise Silveira-Lemos, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Adriano Luiz Souza-Soares, Pollyanna Castro-Silva, Matheus Fernandes Costa-Silva, Pedro Henrique Gazzinelli Guimarães, Helena Barbosa Ferraz, Lúcia Alves Oliveira-Fraga, Mauro Martins Teixeira, Rodrigo Corrêa-Oliveira   +10 more
doaj   +1 more source

The effect of Co-Q10 on allergic rhinitis and allergic asthma

Allergy, Asthma & Clinical Immunology, 2021
Background Allergic asthma is an inflammatory disease resulting from continued or intermittent allergen exposure, and allergic rhinitis can be trigger of asthma.
Qixue Du, Wei Meng, Seyyed Shamsadin Athari, Renzhong Wang   +3 more
doaj   +1 more source