Results 171 to 180 of about 94,786 (284)

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

open access: yesPM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang   +6 more
wiley   +1 more source

Establishment and Comparative Analysis of Radiation‐Induced Liver Disease in Normal and Fibrotic Rat Models

open access: yesPrecision Radiation Oncology, EarlyView.
This study successfully established two novel rat models of radiation‐induced liver disease (RILD), one in healthy livers and the other in TAA‐induced fibrotic livers, providing valuable insights into the combined effects of radiation and pre‐existing fibrosis.
Yanting Jiang   +9 more
wiley   +1 more source

Dynamic modelling of liver-bone axis: A microphysiological approach to hepatic osteodystrophy. [PDF]

open access: yesBioact Mater
Gupta P   +6 more
europepmc   +1 more source

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

open access: yesSmall, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan   +11 more
wiley   +1 more source

The Corrective Role of Melatonin in Synergism of Dark Deprivation and CCl4 Intoxication in the Pathogenesis of Liver Damage a in Rats. [PDF]

open access: yesCurr Issues Mol Biol
Grabeklis SA   +6 more
europepmc   +1 more source

Cognitive and Psychomotor Processing Speed in Medication‐Naïve Individuals With First‐Episode of Psychosis: The Role of Peripheral Inflammatory Markers

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz   +8 more
wiley   +1 more source

TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice. [PDF]

open access: yesMil Med Res
Chen KZ   +11 more
europepmc   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

Proliferation, migration, and differentiation of circulating ILC precursors in HBV infection-associated fibrosis. [PDF]

open access: yesEur J Med Res
Zhu Q   +9 more
europepmc   +1 more source

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