Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]
, 2018 Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M. +5 more
core +1 more source
The Effect of N-Terminal Cyclization on the Function of the HIV Entry Inhibitor 5P12-RANTES. [PDF]
, 2017 Despite effective treatment for those living with Human Immunodeficiency Virus (HIV), there are still two million new infections each year. Protein-based HIV entry inhibitors, being highly effective and specific, could be used to protect people from ...
F Nguyen, Anna +3 more
core +2 more sources
TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]
, 2019 OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core +2 more sources
CCR5 status and metastatic progression in colorectal cancer
OncoImmunology, 2019 Multiple reports have highlighted the importance of the local immunological cellular composition (i.e. the density of effector T cells and macrophage polarization state) in predicting clinical outcome in advanced metastatic stage of colorectal cancer ...
Meggy Suarez-Carmona +22 more
doaj +1 more source
High-Intensity Interval Training and Vitamin D3 Supplementation Decrease CCL-5 and CCR5 Expression In White Adipose Tissue of Diabetic Rats Fed with A High-Fat Diet and Streptozotocin [PDF]
Cell JournalObjective: The purpose of this study was to investigate the effects of 8 weeks of high-intensity interval training (HIIT)and vitamin D3 supplementation on Chemokine (C-C motif) Ligand 5 (CCL-5) and C-C motif chemokine receptor 5(CCR5) in the white ...
Fariba Fallahi +3 more
doaj +1 more source
Metabolic effects of CCL5 deficiency in lean and obese mice
Frontiers in Immunology, 2023 Accumulation and activation of immunocytes in adipose tissues are essential to obesity-induced inflammation and insulin resistance. Chemokines are pivotal for the recruitment of immunocytes in adipose tissue during obesity. Chemokine (C-C motif) ligand 5
Hui Zhou +22 more
doaj +1 more source
Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]
, 2019 Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi +14 more
core +5 more sources
Spinal NF-κB and chemokine ligand 5 expression during spinal glial cell activation in a neuropathic pain model. [PDF]
PLoS ONE, 2015 BACKGROUND:The NF-κB pathway and chemokine (C-C motif) ligand 5 (CCL5) are involved in pain modulation; however, the precise mechanisms of their interactions in chronic neuropathic pain have yet to be established.
Qin Yin +9 more
doaj +1 more source
Heliyon, 2023 Purpose: Chemokine ligand 5 (CCL5), a vital member of the CC chemokine family, plays diverse roles in tumorigenesis, metastasis, and prognosis in various human tumors.
Yanchun Huang +7 more
doaj +1 more source
Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]
, 2013 Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien +6 more
core +2 more sources