Results 91 to 100 of about 16,151,399 (172)

Co‐translational protein targeting to mitochondria in the context of co‐translational protein maturation

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley   +1 more source

Cellular Heterogeneity During Arterial Aging

Aging Cell, Volume 25, Issue 7, July 2026.
Graphical abstract showing arterial cell subpopulations and their functional changes during aging. Transcriptomic profiling studies across species identify age‐associated endothelial, smooth muscle, fibroblast, and immune cell states characterized by inflammation, extracellular matrix remodeling, phenotypic switching, and cellular senescence ...
He Xu, Paul‐Lennard Mendez, Dimitri Kasakovski, Judith Sluimer   +3 more
wiley   +1 more source

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′UTR

Genome Biology, 2019
Background Regulation of the mRNA life cycle is central to gene expression control and determination of cell fate. miRNAs represent a critical mRNA regulatory mechanism, but despite decades of research, their mode of action is still not fully understood.
Ania Wilczynska, Sarah L. Gillen, Tobias Schmidt, Hedda A. Meijer, Rebekah Jukes-Jones, Claudia Langlais, Kari Kopra, Wei-Ting Lu, Jack D. Godfrey, Benjamin R. Hawley, Kelly Hodge, Sara Zanivan, Kelvin Cain, John Le Quesne, Martin Bushell   +14 more
doaj   +1 more source

Not Available

, 2009
Not AvailableNot AvailableNot ...
Not Available
core  

Human DDX6 regulates translation and decay of inefficiently translated mRNAs

eLife
Recent findings indicate that the translation elongation rate influences mRNA stability. One of the factors that has been implicated in this link between mRNA decay and translation speed is the yeast DEAD-box helicase Dhh1p.
Ramona Weber, Chung-Te Chang
doaj   +1 more source

Not Available

, 2014
Not AvailableNot Available.Not ...
Not Available
core   +1 more source

Not Available

, 2013
Not AvailableNot AvailableNot ...
Not Available
core  

Not Available

, 2015
Not AvailableNot AvailableNot ...
Not Available
core   +1 more source

CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury

Journal of Inflammation Research, 2016
Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
doaj  

RNA-binding protein Roq modulates the Drosophila STING antiviral immune response

Cell Investigation
The STING (stimulator of interferon genes) signaling pathway plays a pivotal role in the immune defense against viral infections in a wide range of vertebrates and invertebrates. However, the regulatory picture of this pathway is still incomplete. Herein,
Xianrui Zheng, Yiheng Jin, Chuchu Zhang, Yangyang Zhu, Huimin Guo, Renjie Duan, Yihua Xiao, Baoyi Hu, Yulong Yang, Erwen Ding, Weini Li, Muhammad Abdul Rehman Saeed, Qingshuang Cai, Shanming Ji   +13 more
doaj   +1 more source