Results 81 to 90 of about 16,151,399 (172)
Diverging in Vivo Immune Response Patterns After Oral Food Challenge in Peanut Allergic Adults
Clinical &Experimental Allergy, EarlyView.After the oral food challenge, peanut (PN)‐allergic adults were monitored over 4 weeks, which revealed diverging immune response patterns, with strong responders (SR) exhibiting heightened Ara h 2+ B cell expansion, PN sIgE induction and increasing PN‐specific Tconv. Weak responders (WR) had more activated PN‐specific Tregs.
Florent Fauchère +7 more
wiley +1 more source
, 2018 Not AvailableNews item on "Ber Day and Fruits Show Organized at CAZRI (23 January 2018)"Not ...
Not Available
core +1 more source
Etude structurale du complexe CCR4-NOT
, 2015 MRNA turnover begins with deadenylation where in the poly(A) tail at the 3’ end of the mRNA is removed. Deadenylation is the rate-limiting step of the decay pathway.
Basquin, Jérôme
core
Structural studies of the complex CCR4-NOT
, 2015 Le recyclage des ARN débute par un étape de déadenylation ou la queue poly (A) est enzymatiquement clivée. La deadenylation est l’étape limitante dans le processus de dégradation des ARN.
Basquin, Jérôme
core
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
Advanced Science, Volume 13, Issue 37, 3 July 2026.We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
Generation of Regulatory T Cells Against Islet Neoantigen
European Journal of Immunology, Volume 56, Issue 7, July 2026.Naïve T cells against islet neoantigen exist in peripheral blood that can be primed ex vivo to become regulatory T cells despite the high immunogenic potential of neoantigen. These neoantigen‐induced Tregs show complete suppressive capacity and phenotype indistinguishable from autoantigen‐induced Tregs. Created in BioRender (2026).
Nicoline H. M. Den Hollander +6 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang +5 more
wiley +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open BioDespite the increasing evidence of the role of CCR4‐NOT complex in posttranscriptional gene regulation, relatively little is known about its mode of action. In a search for novel CCR4‐NOT interacting partners, we carried out mass spectrometry analysis of
Shou Soeda +9 more
doaj +1 more source