Results 121 to 130 of about 22,248 (218)

Assessing the adaptive potential of European beech populations to temperature and precipitation along a steep environmental gradient in the south‐eastern Carpathians

Plant Biology, EarlyView.
This study focuses on the identification of candidate SNPs involved in local adaptation to altitude by environmental association analysis conducted on different natural European beech (Fagus sylvatica) populations. Abstract It is necessary to assess the adaptive potential of European beech populations to climate change.
M. Tost, O. Grigoriadou‐Zormpa, S. Wilhelmi, M. Müller, H. Wildhagen, A. L. Curtu, O. Gailing   +6 more
wiley   +1 more source

RNAs and RNA-Binding Proteins in Immuno-Metabolic Homeostasis and Diseases

Frontiers in Cardiovascular Medicine, 2019
The increasing prevalence of worldwide obesity has emerged as a major risk factor for type 2 diabetes (T2D), hepatosteatosis, and cardiovascular disease. Accumulating evidence indicates that obesity has strong inflammatory underpinnings tightly linked to
Esam S. B. Salem, Esam S. B. Salem, Andrew D. Vonberg, Vishnupriya J. Borra, Rupinder K. Gill, Takahisa Nakamura, Takahisa Nakamura, Takahisa Nakamura, Takahisa Nakamura   +8 more
doaj   +1 more source

The roles of the exoribonucleases DIS3L2 and XRN1 in disease [PDF]

, 2016
RNA degradation is a vital post-transcriptional process which ensures that transcripts are maintained at the correct level within the cell. DIS3L2 and XRN1 are conserved exoribonucleases which are critical for the degradation of cytoplasmic RNAs ...
Jones, Christopher I, Newbury, Sarah F, Pashler, Amy L, Towler, Ben   +3 more
core   +1 more source

SuperSAGE analysis of the Nicotiana attenuata transcriptome after fatty acid-amino acid elicitation (FAC): identification of early mediators of insect responses [PDF]

, 2010
Background Plants trigger and tailor defense responses after perception of the oral secretions (OS) of attacking specialist lepidopteran larvae. Fatty acid-amino acid conjugates (FACs) in the OS of the Manduca sexta larvae are necessary and sufficient to
Paola A Gilardoni, Stefan Schuck, Ruth Jüngling, Björn Rotter, Ian T Baldwin, Gustavo Bonaventure   +5 more
core   +2 more sources

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

Periodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh, Andrea Mombelli, Frank Schwarz, Jan Derks   +3 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, Volume 20, Issue 3, Page 753-778, March 2026.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A novel class of microRNA-recognition elements that function only within open reading frames. [PDF]

, 2018
MicroRNAs (miRNAs) are well known to target 3' untranslated regions (3' UTRs) in mRNAs, thereby silencing gene expression at the post-transcriptional level.
A Aizer, A Helwak, A Jakymiw, A Lal, AE Pasquinelli, AJ Giraldez, Alexander Dobin, AM Duursma, AR Buskirk, AR Quinlan, B Langmead, Bing Zhou, CJ Decker, CJ Shoemaker, CJ Woolstenhulme, CP Petersen, Dehe Wang, DP Bartel, DT Humphreys, E Huntzinger, EL Nostrand Van, GB Loeb, Guangqiao Liu, H Guo, HA Meijer, HO Iwakawa, I Behm-Ansmant, I Elcheva, J Hausser, J Liu, J Liu, JH Kim, Jie Zhou, JJ Forman, JP Broughton, K Seggerson, KA O’Donnell, Kai Zhang, L Wu, Ligang Wu, M Hafner, M Kouwenhove van, M Rehmsmeier, MD Robinson, MK Doma, ML Donnelly, N Rajewsky, NT Schirle, PA Maroney, Qian Zhao, R Ishimura, R Ishimura, R Parker, Ran Cao, RS Pillai, S Bagga, S Djuranovic, S Grosswendt, S Gu, S Jonas, S Nottrott, S Takagi, SN Bhattacharyya, SW Chi, SW Eichhorn, Timothy Nilsen, TT Tat, V Presnyak, W Filipowicz, Wen Ruan, X Adiconis, Xiang-Dong Fu, Xiaorong Zhang, Y Ishigaki, Y Liao, Y Tay, Y Wang, Y Xue, Y Zhao, Ya Zhao, Yan Qin, Yu Zhou, Yuanchao Xue, Z Cai, Zhiqiang Cai, Zonggui Chen   +85 more
core   +2 more sources

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 127-143, March 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Roles of the yeast Ccr4‐Not complex in regulating transcription

The FASEB Journal, 2010
The highly conserved Ccr4‐Not complex has been ascribed many functions, from transcription regulation to mRNA decay. Initial studies described a role of this complex in preinitiation complex formation, but a number of studies have clearly shown Ccr4‐Not mediates deadenylation of mRNAs and
Arnob Dutta, Jennifer A Kruk, David S Gilmour, Joseph C Reese   +3 more
openaire   +1 more source

Genome-wide studies of mRNA synthesis and degradation in eukaryotes [PDF]

, 2012
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic transcription producing results for thousands of genes at every step of mRNA life.
Adelman, Airoldi, Alberola, Alon, Aragon, Arava, Baugh, Bernstein, Berretta, Carrillo Oesterreich, Castells-Roca, Chang, Chatenay-Lapointe, Choder, Churchman, Core, Dahan, Doma, Dori-Bachash, Exinger, Fan, Fan, Farago, Filipovska, Galburt, García-Martínez, Gerber, Glesne, Goler-Baron, Grigull, Guenther, Guo, Hah, Harel-Sharvit, Hayles, Hirayoshi, Hogan, Holstege, Jona, José E. Pérez-Ortín, Keene, Kenzelmann, Kim, Kim, Kireeva, Kruk, Kuehner, Kurischko, Kwapisz, Lahudkar, Lardenois, Lefrancois, Legen, Lola de Miguel-Jiménez, Lotan, Lotan, Martens, Mason, Mavrich, Mayer, Miller, Molin, Molina-Navarro, Morillo-Huesca, Muse, Neil, Nelson, Parker, Pelechano, Pelechano, Pelechano, Perales, Pérez-Ortín, Pérez-Ortín, Pérez-Ortín, Rabani, Radonjic, Rodriguez-Gil, Romero-Santacreu, Schwanhausser, Sebastián Chávez, Selitrennik, Selth, Shalem, Shalem, Shema, Slavov, Struhl, Tenenbaum, Terzi, Tous, van Bakel, van Dijk, Venters, Vergara, Voliotis, Wade, Wang, Warner, Wei, Wilbert, Xu, Yassour, Zeitlinger   +103 more
core   +2 more sources