Results 101 to 110 of about 13,668 (163)

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 6, Page 1250-1270, March 2026.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Comparison Between Phenotypic Profile and Functional Aspects of IL‐9‐Producing Lymphocytes, Th17 and Tfh of Individuals From Endemic and Non‐Endemic Areas for Hookworm Infection

open access: yesParasite Immunology, Volume 48, Issue 3, March 2026.
ABSTRACT Hookworm infections remain a major public health concern in endemic areas, modulating both the adaptive and innate immune systems. While the type 2 response is well‐characterised, the roles of T follicular helper (Tfh), Th17, and IL‐9‐producing lymphocytes remain poorly defined.
Yvanna Louise Di Christine Oliveira   +10 more
wiley   +1 more source

CCR4-NOT Complex 2-A Cofactor in Host Cell for Porcine Epidemic Diarrhea Virus Infection. [PDF]

open access: yesGenes (Basel), 2022
Wang J   +16 more
europepmc   +1 more source

Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2. [PDF]

open access: yesRNA Biol, 2022
Suzuki T   +8 more
europepmc   +1 more source

CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury

open access: yesJournal of Inflammation Research, 2016
Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
doaj  

Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex

open access: yesRNA
The sequence-specific RNA-binding protein Pumilio controls Drosophila development; however, the network of mRNAs that it regulates remains incompletely characterized. In this study, we utilize knockdown and knockout approaches coupled with RNA-Seq to measure the impact of Pumilio on the transcriptome of Drosophila cells in culture.
Rebecca J. Haugen   +10 more
openaire   +2 more sources

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