Results 111 to 120 of about 13,668 (163)

Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes

Journal of Inflammation Research
Tomokazu Yamaguchi,1,2,* Ryo Ozawa,2,3,* Takafumi Minato,2 Midori Hoshizaki,4 Yutaro Kammura,1,5 Kazuma Okawara,1,6 Yousef A Khalil,1 Masafumi Nakamura,6 Ken Yamaura,5 Masayuki Fukuda,3 Yumiko Imai,4 Keiji Kuba1,2 1Department of Pharmacology ...
Yamaguchi T, Ozawa R, Minato T, Hoshizaki M, Kammura Y, Okawara K, Khalil YA, Nakamura M, Yamaura K, Fukuda M, Imai Y, Kuba K   +11 more
doaj  

Composition and function of Ccr4-Not protein complexes

, 2010
Ccr4-Not protein complexes are evolutionarily conserved and have important functions in mRNA regulatory processes. Strict regulation of mRNA’s is important for cells since they form the central connection between the genetic information in the nucleus and active protein production in the cytoplasm.
openaire   +1 more source

Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex. [PDF]

Genes (Basel), 2021
Munakata F, Suzawa M, Ui-Tei K.
europepmc   +1 more source

The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. [PDF]

Adv Sci (Weinh), 2021
Dai XX, Jiang Y, Gu JH, Jiang ZY, Wu YW, Yu C, Yin H, Zhang J, Shi QH, Shen L, Sha QQ, Fan HY.   +11 more
europepmc   +1 more source

DDX24 modulates angiogenesis by promoting CCR4-NOT complex-dependent mRNA decay. [PDF]

Nucleic Acids Res
He S, Li B, Chen F, Huang J, Dong Y, Liu S, Liu C, Zhang Q, Wang L, Shan H, Gong Y, Yang J, He H.   +12 more
europepmc   +1 more source

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity
Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the Cnot1 gene, which encodes an essential scaffold subunit of the CCR4–NOT deadenylase complex in adipose tissues (Cnot1-AKO mice) and we examined the role of CCR4–NOT in adipocyte function.
openaire  

The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]

Nucleic Acids Res
Caulier G, Siblini J, Sène L, Mauxion F, Séraphin B.   +4 more
europepmc   +1 more source

Corrigendum: Specific roles for the Ccr4-Not complex subunits in expression of the genome. [PDF]

RNA
Azzouz N, Panasenko OO, Deluen C, Hsieh J, Theiler G, Collart MA.   +5 more
europepmc   +1 more source

Regulation of sod1 mRNA and protein abundance by zinc in fission yeast is dependent on the CCR4-NOT complex. [PDF]

J Biol Chem
Weeks AT, Bird AJ.
europepmc   +1 more source

Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes. [PDF]

Science
Zhu X, Cruz VE, Zhang H, Erzberger JP, Mendell JT.   +4 more
europepmc   +1 more source