Results 131 to 140 of about 15,618 (178)

The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs.

Development, 2023
Soeda S, Oyama M, Kozuka-Hata H, Yamamoto T.   +3 more
europepmc   +1 more source

Composition and function of Ccr4-Not protein complexes

, 2010
Ccr4-Not protein complexes are evolutionarily conserved and have important functions in mRNA regulatory processes. Strict regulation of mRNA’s is important for cells since they form the central connection between the genetic information in the nucleus and active protein production in the cytoplasm.
Lau,N.C., Cancer, Regenerative Medicine and Stem Cells, CMM Sectie Molecular Cancer Research, Timmers, Marc   +4 more
openaire   +1 more source

Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes

Journal of Inflammation Research
Tomokazu Yamaguchi,1,2,* Ryo Ozawa,2,3,* Takafumi Minato,2 Midori Hoshizaki,4 Yutaro Kammura,1,5 Kazuma Okawara,1,6 Yousef A Khalil,1 Masafumi Nakamura,6 Ken Yamaura,5 Masayuki Fukuda,3 Yumiko Imai,4 Keiji Kuba1,2 1Department of Pharmacology ...
Yamaguchi T, Ozawa R, Minato T, Hoshizaki M, Kammura Y, Okawara K, Khalil YA, Nakamura M, Yamaura K, Fukuda M, Imai Y, Kuba K   +11 more
doaj  

Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex. [PDF]

Genes (Basel), 2021
Munakata F, Suzawa M, Ui-Tei K.
europepmc   +1 more source

Biochemical analysis of the nuclease module of the human Ccr4-Not deadenylase complex [PDF]

In eukaryotic cells, the shortening and removal of the poly(A) tail (deadenylation) of cytoplasmic mRNA is a key step in mRNA degradation. The Ccr4-Not complex is well-characterised as a major deadenylase enzyme involved in mRNA deadenylation.
Maryati, Maryati
core   +2 more sources

The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. [PDF]

Adv Sci (Weinh), 2021
Dai XX, Jiang Y, Gu JH, Jiang ZY, Wu YW, Yu C, Yin H, Zhang J, Shi QH, Shen L, Sha QQ, Fan HY.   +11 more
europepmc   +1 more source

DDX24 modulates angiogenesis by promoting CCR4-NOT complex-dependent mRNA decay. [PDF]

Nucleic Acids Res
He S, Li B, Chen F, Huang J, Dong Y, Liu S, Liu C, Zhang Q, Wang L, Shan H, Gong Y, Yang J, He H.   +12 more
europepmc   +1 more source

The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]

Nucleic Acids Res
Caulier G, Siblini J, Sène L, Mauxion F, Séraphin B.   +4 more
europepmc   +1 more source

Insulin-Degrading Enzyme Regulates mRNA Processing and May Interact with the CCR4-NOT Complex. [PDF]

Cells
Bertocci B, Yilmaz A, Waeckel-Énée E, Guerrera C, Roger K, Touré L, van Endert PM.   +6 more
europepmc   +1 more source

Corrigendum: Specific roles for the Ccr4-Not complex subunits in expression of the genome. [PDF]

RNA
Azzouz N, Panasenko OO, Deluen C, Hsieh J, Theiler G, Collart MA.   +5 more
europepmc   +1 more source