RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation. [PDF]
Poetz F +10 more
europepmc +1 more source
Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2. [PDF]
Suzuki T +8 more
europepmc +1 more source
CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury
Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
doaj
Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex
The sequence-specific RNA-binding protein Pumilio controls Drosophila development; however, the network of mRNAs that it regulates remains incompletely characterized. In this study, we utilize knockdown and knockout approaches coupled with RNA-Seq to measure the impact of Pumilio on the transcriptome of Drosophila cells in culture.
Rebecca J. Haugen +10 more
openaire +2 more sources
Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]
Cooper, Andrea +3 more
core +2 more sources
Tomokazu Yamaguchi,1,2,* Ryo Ozawa,2,3,* Takafumi Minato,2 Midori Hoshizaki,4 Yutaro Kammura,1,5 Kazuma Okawara,1,6 Yousef A Khalil,1 Masafumi Nakamura,6 Ken Yamaura,5 Masayuki Fukuda,3 Yumiko Imai,4 Keiji Kuba1,2 1Department of Pharmacology ...
Yamaguchi T +11 more
doaj
Composition and function of Ccr4-Not protein complexes
Ccr4-Not protein complexes are evolutionarily conserved and have important functions in mRNA regulatory processes. Strict regulation of mRNA’s is important for cells since they form the central connection between the genetic information in the nucleus and active protein production in the cytoplasm.
openaire +1 more source
Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex. [PDF]
Munakata F, Suzawa M, Ui-Tei K.
europepmc +1 more source
The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. [PDF]
Dai XX +11 more
europepmc +1 more source

